超短效与短效胰岛素强化治疗糖尿病的比较

目的:观察超短效人胰岛素类似物赖脯胰岛素(优泌乐,Lispro)与短效胰岛素诺和灵R(Novolin R)在强化治疗中的疗效差异。方法:60名2型糖尿病患者随机分为两组,胰岛素泵治疗1周,观察两组治疗前后不同时间点血糖值变化、达标时间、胰岛素用量及有无低血糖发生。结果:Lispro组较Novolink R组血糖达标时间短、胰岛素用量少、两组均未发生低血糖。结论:在胰岛素泵强化治疗中Lispro更具优势。

Study of Insulin Lispro and Novolin R in Intensification Therapy on Diabetes Mellitus

Objective:To observe the difference of therapeutic effect between supershort-effect insulin analog lispro and short- effect insulin novolin R on diabetes patients.Method:Sixty type 2 diabetes mellitus patients were divided into two groups and received insulin pump therapy for 2 weeks.The plasma glucose at different time after therapy,period of reaching target,total insulin dosage and whether hypoglycaemia happened were observed.Result:Period of reaching target of Lispro group was shorter than novolin R group, and total insulin dosage was less than novolin R group.There were no hypoglycaemia happened in neither groups.Conclusion:Lispro had an advantage comparing with novolin R in insulin pump intensification therapy.