| 三孢布拉霉发酵产番茄红素的研究进展 |
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| 引用本文： | 王强,余晓斌. 三孢布拉霉发酵产番茄红素的研究进展[J]. 微生物学通报, 2015, 42(2): 420-426 |
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| 作者姓名： | 王强 余晓斌 |
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| 作者单位： | 江南大学生物工程学院 工业生物技术教育部重点实验室 江苏 无锡 214122,江南大学生物工程学院 工业生物技术教育部重点实验室 江苏 无锡 214122 |
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| 基金项目： | 江苏省自然科学基金项目(No. BK20130130) |
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| 摘 要： | 番茄红素是一种重要的类胡萝卜素,在生物体中具有抗氧化、抗衰老、提高免疫力等生理功能。虽然已经有部分企业实现了番茄红素的工业化生产,但产量仍然是制约三孢布拉霉发酵生产番茄红素的重要因素。在本实验室研究的基础上,本文结合近年来国内外学者的研究成果,从遗传育种、发酵工艺优化、化学调控等方面综述了提高三孢布拉霉中番茄红素产量的研究进展,并展望了未来的研究方向。
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| 关 键 词： | 番茄红素 三孢布拉霉 菌种选育 工艺优化 化学调控 |
Advance in production of lycopene by Blakeslea trispora |
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| WANG Qiang and YU Xiao-bin. Advance in production of lycopene by Blakeslea trispora[J]. Microbiology China, 2015, 42(2): 420-426 |
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| Authors: | WANG Qiang and YU Xiao-bin |
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| Affiliation: | The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China and The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China |
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| Abstract: | Lycopene is a member of important carotenoids with antioxidation, anti-aging, immunity enhancement, and other physiological functions. Although commercial production of lycopene has been realized in some enterprise, poor lycopene production remains the key restricting factor for lycopene biosynthesis by Blakeslea trispora. Combining with the latest achievements of lycopene production by B. trispora, this mini-review summarized the genetic breeding of strain, the optimization of fermentation process, chemical regulation, and the prospects of future research. |
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| Keywords: | Lycopene Blakeslea trispora Genetic breeding Process optimization Chemical regulation |
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