针药结合对先天愚型儿童智商和社会适应行为的影响

目的:观察针刺配合口服真人益智宝对先天愚型儿童智商(IQ)及社会适应行为(ADQ)的影响。方法:将50例先天愚型儿童分为针药结合组与药物组。针刺以头三针为主,配合体针,药物采用口服香港宗歧氏药厂生产的真人益智宝。治疗前后均采用斯坦福-比奈智力量表、儿童社会适应能力量表对患儿进行IQ、ADQ测定。结果:针药结合及单纯口服药物均能提高先天愚型患儿的IQ及ADQ水平(均P<0·01);针药结合对IQ、ADQ的影响较单纯口服药物更为明显(P<0·01)。结论:针刺配合口服真人益智宝能提高先天愚型儿童智商及社会适应能力水平,其疗效优于单纯口服真人益智宝。

Effect of Acupuncture Combined with Herbal Medicines on Intelligence Quotient and Adaptive Behavior Quotient in Infant Patients with Down''''s Syndrome

Objective: To observe the effect of acupuncture combined with patent herbal drug (Zhen Ren Yi Zhi Bao, Treasured Drug for improving intelligence) on the intelligence quotient (IQ) and adaptive behavior quotient (ADQ) in infant patients with Down's Syndrome. Methods: Fifty child patients with Down's Syndrome (mongolism) were randomly divided into acupuncture plus medication (n=30) and medication (n=20) groups. For patients of acupuncture plus medication group, Zhisanzhen (point 1: the cross-point between the forehead hair border and the midline of the head; point 2 and 3: 3 cun left and right to point 1), Sishenzhen 4 points 1.5 cun left, right, superior and inferior respectively to Baihui (GV 20), Naosanzhen Naohu (GV 17), bilateral Naokong (GB 19), Shouzhizhen Neiguan (PC 6), Shenmen (HT 7) and Laogong (PC 8), Hegu (LI 4), etc were punctured, once daily, 5 times a week. For medication, patients of two groups were asked to take Zhen Ren Yi Zhi Bao, 2-3 granules/time (b.i.d.), with 1 month being a therapeutic course, two courses altogether. The interval between two courses was one month. IQ and ADQ tests were conducted before and after the treatment. Results: After the treatment, both IQ and ADQ in acupuncture plus medication group all increased obviously (IQ: 60.58±7.46 vs 51.27±5.55; ADQ: 61.96±6.67 vs 52.42±5.47, P<0.01), while in medication group, both IQ and ADQ increased significantly (IQ: 56.40±6.92 vs 51.55±5.90; ADQ: 58.35±6.24 vs 53.25±5.27, P<0.01). Comparison between two groups showed that the increased fraction of IQ and ADQ of acupuncture plus medication group were significantly higher than those of medication group (P<0.01). Conclusion: Acupuncture combined with Zhen Ren Yi Zhi Bao can significantly improve IQ and ADQ of patients with Down's syndrome, and the therapeutic effect of acupuncture plus medication is markedly better than that of simple medication.