早期肠内营养对重症急性胰腺炎患者机体综合状态的影响

目的探讨早期肠内营养对重症急性胰腺炎患者机体综合状态的影响。方法选取2010年1月至2012年12月于南充市中心医院进行治疗的96例重症急性胰腺炎患者为研究对象,将其随机分为对照组48例和观察组48例,对照组采用全胃肠外营养支持,观察组则采用早期肠内营养支持,将两组患者干预前与干预后1周、2周的免疫状态指标、营养状态指标及炎性状态指标进行比较。结果观察组干预后1周、2周的免疫状态指标、营养状态指标及炎性状态指标均显著优于对照组,对照组干预后2周明显优于干预前,差异均有统计学意义（P〈0.05）。结论早期肠内营养对重症急性胰腺炎患者机体综合状态的影响更为积极,有助于控制患者的炎性状态及调整机体免疫、营养状态。

Influence of early enteral nutrition for the body comprehensive state of patients with sgvere acu~ paucreatitis.

Objective To study the influence of early enteral nutrition for the body comprehensive state of patients with severe acute pancreatitis. Methods A total of 96 patients with severe acute pancreatitis from January 2010 to December 2012 were selected and randomly divided into control group （48 cases） and observation group （48 cases）.and Patients in the control group were intervened with total parenteral nutrition support, and patients in the ob- servation group were intervened with early enteral nutrition support. The immune state indexes, nutritional state index- es and inflammatory state indexes of two groups before the intervention and at 1~, 2~ week after the intervention were compared. Results The immune state indexes, nutritional state indexes and inflammatory state indexes in observa- tion group at 1~ and 2~ week after the intervention were all significantly better than those in control group, those index- es of observation group at 2＂d week after the intervention were obviously better than those before the intervention, all with P〈0.05. Conclusion The influence of early enteral nutrition is more active for the body comprehensive state of patients with severe acute pancreatitis;which is helpful for controlling of inflammatory state and adjusting of immune state and nutritional state.