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头孢哌酮与莫西沙星治疗肺部感染的疗效对比
引用本文:杨炜,陈力. 头孢哌酮与莫西沙星治疗肺部感染的疗效对比[J]. 中国医院用药评价与分析, 2009, 0(7): 540-541
作者姓名:杨炜  陈力
作者单位:[1]成都市第六人民医院呼吸内科,成都市610051 [2]成都铁路中心医院老年科,成都市610081
摘    要:目的:比较头孢哌酮与莫西沙星治疗肺部感染的疗效及其安全性。方法:共选入肺部感染住院患者120例,随机分为两组,其中应用头孢哌酮治疗60例、莫西沙星治疗60例。结果:头孢哌酮组有效率86.7%,莫西沙星组有效率93.3%;对致病菌株的清除率分别为83%和90.8%;不良反应发生率分别为5%与3.3%,两者临床疗效无明显差异(P〉0.05)。结论:头孢哌酮与莫西沙星都是安全有效治疗肺部感染的药物。

关 键 词:头孢哌酮  莫西沙星  肺部感染  临床疗效  安全性

Cefoperazone vs. Moxifloxacin in the Treatment of Pulmonary Infection
YANG Wei,CHEN Li. Cefoperazone vs. Moxifloxacin in the Treatment of Pulmonary Infection[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2009, 0(7): 540-541
Authors:YANG Wei  CHEN Li
Affiliation:1. Dept. of Respiratory Medicine, Chengdu Sixth People's Hospital, Chengdu 610015, China; 2.Dept. of Geriatrics, Chengdu Railroad Central Hospital, Chengdu 610082, China)
Abstract:OBJECTIVE:To evaluate the therapeutic efficacy and adverse reactions of cefoperazone vs.moxifloxacin for pulmonary infection.METHODS:120 inpatients with pulmonary infection were randomly assigned to receive cefoperazone(n=60) or moxifloxacin(n=60).RESULTS:There were no significant differences between the cefoperazone group and the moxifloxacin group in clinical efficacy(P〉0.05)(effective rate:86.7% vs.93.3%;bacterial clearance rate:83% vs.90.8%;incidence of adverse reactions:5% vs.3.3%) CONCLUSION:Both cefoperazone and moxifloxacin are safe and effective for patients with pulmonary infection.
Keywords:Cefoperazone  Moxifloxacin  Pulmonary infection  Clinical efficacy  Safety
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