高血压病患者脉压和颈动脉粥样硬化关系及对预后的影响

目的通过对不同脉压(PP)值的高血压患者临床资料的探究,分析PP与其颈动脉粥样硬化、预后等的相关性。方法将我院接诊的128例高血压患者作为探讨主体,以PP是否低于60 mm Hg为分类标准,其中低于60 mm Hg的65例设为A组,等于或大于60 mm Hg的63例设为B组,对比两组检查结果。结果两组TC、HDL、TG、Cr、UA方面无显著差异(P>0.05),而其SBP、Glu、LDL组间差异具显著性(P<0.05);B组IMT、斑块Crouse积分与检出率均明显较A组高(P<0.05);B组并发症总发生率明显较高(P<0.05)。结论高血压患者PP值可折射出其动脉粥样硬化程度,PP值高者发作心脑血管病的机率更大,这为预测与改善预后提供了可靠依据。

Pulse Pressure in Patients with Hypertension and Carotid Atherosclerosis and Its Impact on the Prognosis

Objective To analyze the correlations of pulse pressure（PP） and carotid atherosclerosis, prognosis in patients with hypertension. Methods 128 patients with hypertension were selected as the research objects, and divided into group A（PP 60 mm Hg, n =65） and group B（PP ≥60 mm Hg, n = 63）. The inspection results of the two groups were compared. Results There was no statistical difference in TC, HDL, TG, Cr and UA between the two groups（P 0.05）, but there was statistical difference in SBP, Glu and LDL between the two groups（P 0.05）. IMT, plaque crouse score and detection rate of group B were higher than those of group A（P 0.05）. The incidence of complications of group B was significantly higher than that of group A（P 0.05）. Conclusions The PP value of patients with hypertension can reflect the degree of atherosclerosis. Patient with greater PP value has higher probability of onset of cardiovascular disease.This provides a reliable basis for predicting and improving the prognosis.