血清胆红素在冠心病发病过程中的作用

目的：探讨血清胆红素水平对冠心病的影响。方法：对健康组及冠心病组进行血清脂质、脂蛋白的测定，并同时检测冠心病组、其他疾病组、健康组的血清胆红素水平。结果：冠心病组的TG、LDL－C、apB、LP（a)较对照组显著增高，HDL－C、apoA、较对照组减少（P＜0．01），TC亦较对照组增高但无统计学意义（P＞0．05），同时冠心病组的总胆红素、直接胆红素及间接胆红素较正常对照组降低（P＜0．05）；其他疾病组这三项指标与正常对照组无显著差异（P＞0．05）。结论：低浓度的胆红素是冠心病的独立危险因素。

The role of serum bilirubin in coronary heart disease

Objective: To study the role of serum bilirubin in coronary heart disease (CHD).Method: The concentrations of blood - cipid and lipoprotein were determined in normal group and CHD group. The Concentration of serum bilirubin was determined in CHD group, other disease group and normal group. Result:The concentrations of TG, LDL-C, apB and LP(a) were remarkably higher in CHD group than in normal group, but the concentrations of HDL-C and apoA were lower in CHD group than in normal group (respectively, P<0.01).The concentration of TG was only little higher in CHD group than in normal group (P>0.05). The concentrations of total bilirubin, direct bilirubin and indirect bilirubin were lower in CHD group than in normal group (P<0.05), but there were not different about serum bilirubin in other disease and in normal group (P>0.05). Conclusion:The low concentration of serum bilirubin was an independent dangerous factor for CHD.