多位点酶电泳法(ET)用于我国A群脑膜炎奈氏菌的分型及流行病学意义

应用多位点酶电泳(ET)分型法从我国183株A群脑膜炎奈氏菌中分出24个ET型,其中ET₃、ET₁₃为70年代以来在我国引起流脑流行的优势型别。在不同的流行期中优势型别不相同。每一次流行只和一个ET优势型别有关。在流行间歇期,存在许多地方性的ET型别的菌株引起的发病和健康带菌者。

Method of Multilocus Enzyme Electrophoresis for Typing Neisseria Meningitidis Serogroup A in China and It's Significance in Epidemiology

A new, more perfect taxonomic method the multilocus enzyme electrophoresis has recently been developed to type Neisseria meningitidise serogroup A strains in China isolated from 1956-1987 and to study the epidemiological relationship of the types. 183 strains could be divided into 24 ET types, among which ETs, ET18 were found predominant in epidemics occurred in last two decades respectively. Different predominant ET types were found in different epidemic period and only one predominant ET type existed in each period. The cases and carriers occurred in the interepidemic stage and in some places. Their strains belonged to some endemic ET types.