| Expression of metallothionein-3 gene associated with lung adenocarci-noma |
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| 作者姓名： | 卢继忠 黄盛东 李继喜 季朝能 于伟勇 徐志云 |
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| 作者单位： | Cardiac-thoracic Department Changhai Hospital，Second Military Medical University，Cardiac-thoracic Department，Changhai Hospital，Second Military Medical University，State Key Laboratory of Genetic Engineering，School of Life Sciences，Fudan University，State Key Laboratory of Genetic Engineering，School of Life Sciences，Fudan University，Cardiac-thoracic Department，Changhai Hospital，Second Military Medical University，Cardiac-thoracic Department，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Shanghai 200433，China，Shanghai 200433，China，Shanghai 200433，China，Shanghai 200433，China，Shanghai 200433，China |
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| 摘 要： | Objective:To explore the role of metallothionein-3 gene in lung adenocarcinoma. Methods: cDNA microarray and northern blots analysis were used to study the expression of metallothionein-3 in lung adenocarcinoma. Results: The results of cDNA microarray showed that metallothionein-3 gene was expressed highly to normal lung tissues at the average ratio of 7. 8 (Cy5/Cy3) in lung adenocarcinoma tissues. Northern blots confirmed the ratio changes detected from the microarray. Conclusion: Metallothionein-3 may play an important role in the lung adenocarcinoma development.
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Expression of metallothionein-3 gene associated with lung adenocarcinoma |
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| LU Ji-zhong,HUANG Sheng-dong,LI Ji-xi,JI Chao-neng,YU Wei-yong,XU Zhi-yun.Expression of metallothionein-3 gene associated with lung adenocarci-noma[J].Journal of Medical Colleges of PLA(China),2006,21(5). |
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| Authors: | LU Ji-zhong HUANG Sheng-dong LI Ji-xi JI Chao-neng YU Wei-yong XU Zhi-yun |
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| Affiliation: | Shanghai Xiehe Hospital Cardiac-thoracic Department,Changhai Hospital,Second Military Medical University,Shanghai,200433,China State Key Laboratory of Genetic Engineering,School of Life Sciences,Fudan University,Shanghai,200433,China State Key Laboratory of Genetic Engineering,School of Life Sciences,Fudan University,Shanghai,200433,China Cardiac-thoracic Department,Changhai Hospital,Second Military Medical University,Shanghai,200433,China State Key Laboratory of Genetic Engineering,School of Life Sciences,Fudan University,Shanghai,200433,China |
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| Abstract: | Objective:To explore the role of metallothionein-3 gene in lung adenocarcinoma. Methods:cDNA microarray and northern blots analysis were used to study the expression of metallothionein-3 in lung adenocarcinoma. Results: The results of cDNA microarray showed that metallothionein-3 gene was expressed highly to normal lung tissues at the average ratio of 7.8 (Cy5/Cy3) in lung adenocarcinoma tissues. Northern blots confirmed the ratio changes detected from the microarray. Conclusion: Metallothionein-3 may play an important role in the lung adenocarcinoma development. |
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| Keywords: | metallothionein-3 lung adenocarcinoma cDNA microarray Northern blots |
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