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| 白色念珠菌分泌物对人类多发性骨髓瘤细胞作用机制的初步研究 | |
| 引用本文： | 刘静,胡维新,韦超凡,刘艳平,何莉芳. 白色念珠菌分泌物对人类多发性骨髓瘤细胞作用机制的初步研究[J]. 中国现代医学杂志, 2002, 12(7): 16-17 |
| 作者姓名： | 刘静 胡维新 韦超凡 刘艳平 何莉芳 |
| 作者单位： | 1. 中南大学湘雅医学院分子生物研究中心,长沙,410078 2. 中南大学湘雅医学院免疫学教研室 3. 中南大学湘雅医学院生物学教研室 |
| 摘 要： | 目的：探讨白色念珠菌（ID16VI）分泌物对人类多发性骨髓瘤细胞（ARH-77）的作用。方法：荧光染色观察对照组和实验组细胞形态变化；FCM检测凋亡细胞百分率。结果：荧光显微镜下观察到白色念珠菌分泌物处理组的凋亡细胞增多；FCM检测实验组凋亡细胞百分率上升。结论：白色念珠菌分泌物能促进ARH-77细胞凋亡。 |
| 关 键 词： | 白色念珠菌分泌物 多发性骨髓瘤细胞 细胞凋亡 |
| 修稿时间： | 2002-01-05 |
MECHANISMS INDUCED BY THE SECRETION OF CANDIDA ALBICANS IN HUMAN MULTIPLE MYELOMA CELLS |
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| Liu Jing,Hu Weixin,Wei Chaofan Research Center of Molecular Biology,Xiangya Medical College,Central South University,Changsha Liu Yanping,He Lifang. MECHANISMS INDUCED BY THE SECRETION OF CANDIDA ALBICANS IN HUMAN MULTIPLE MYELOMA CELLS[J]. China Journal of Modern Medicine, 2002, 12(7): 16-17 | |
| Authors: | Liu Jing Hu Weixin Wei Chaofan Research Center of Molecular Biology Xiangya Medical College Central South University Changsha Liu Yanping He Lifang |
| Affiliation: | Liu Jing,Hu Weixin,Wei Chaofan Research Center of Molecular Biology,Xiangya Medical College,Central South University,Changsha 410078 Liu Yanping,He Lifang Department of Biology,Xiangya Medical College,Central South University |
| Abstract: | Objective:To determine the mechanisms induced by the secretion of candida albicans in human multiple myeloma cells.Methods:Apoptotic cells were observed by fluoresence microscopy.The rate of sub_G 1 phase cells was analyzed by flow cytometry.Results:Our results suggested that the rate of apoptosis cells and sub_G 1phase cells were increased in experimental group.Conclusions:The sercetion of candida albicans can induce the apoptosis of ARH-77 cells. |
| Keywords: | Secretion of Candida Albicans Multiple Myeloma Cell Apoptosis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
