电氧化异丙肾上腺素的纳米复合电催化剂：用作传感器

在金纳米粒子(AuNPs)上经苯硫酚衍生物(3,4二羟基苯基-偶氮-苯硫酚, DAT)自组装制得了一种新型纳米复合物,用于修饰玻璃碳电极(GCE/AuNP-DAT).采用循环伏安法研究了该新型电极的性质,并将其用作异丙肾上腺素(IP)电催化剂,考察了该纳米复合物的电催化活性,从而得到反应机理和催化反应速率常数.由于GCE/AuNP-DAT电极对尿酸氧化没有电催化活性,因此可将IP的氧化信号从该改进电极中分离出来,从而排除了尿酸对IP测定的干扰.该电极可作为传感器,当用于差动脉冲伏安法测定IP时,线性动态范围为1.0–1500.0μmol/L,检测极限为0.46μmol/L.

A nanocomposite electrocatalyst for the electro-oxidation of isoproterenol and its application as a sensor

A novel nanocomposite (GCE/AuNP-DAT) was fabricated via the self-assembly of a thiophenol de-rivative (3,4-dihydroxyphenyl-azo-2-thiophenol, DAT) on a gold nanoparticle (AuNP)-modified glassy carbon electrode (GCE). This novel modified electrode was investigated using cyclic voltam-metry, and the electrode was applied for the electrocatalysis of isoproterenol (IP). The electrocata-lytic activity of this nanocomposite was studied, and the reaction mechanism and catalytic rate constant were determined for IP. The GCE/AuNP-DAT did not show any electrocatalytic activity for the oxidation of uric acid, and the oxidation signal for IP was therefore not affected by the presence of uric acid at this electrode;any interference from uric acid in the detection of IP was eliminated by the modified electrode. This electrode was applied as a sensor, and differential pulse voltammetry data obtained using this sensor exhibited a linear dynamic range of 1–1500 μmol/L and a detection limit of 0.46 μmol/L for IP.