天灸疗法对支气管哮喘患者血浆SP和VIP含量的影响

采用天灸疗法治疗 2 7例支气管哮喘患者 ,并与针刺法进行对照研究 ,观察两组的疗效及治疗前后血浆SP和VIP含量的变化情况。结果表明 ,两组的临床疗效无显著性差异。两组均能降低患者的血浆SP含量及提高VIP含量 ,但以实验组尤为明显

The Effect of Medicinal Vesiculation Therapy on Plasma SP and VIP Contents in Bronchial Asthma Patients

Objective: To observe the effect of medicinal vesiculation (MV) on plasma substance P (SP) and vasoactive intestinal peptide (VIP) contents in patients with brachial asthma. Methods: 52 asthma patients were randomly divided into MV group (n=27) and acupuncture group (n=25). Feishu (BL 13), Dingchuan (EX B 1), Fengmen (BL 12), Dazhui (GV 14), etc were used. In MV group, Chinese medicinal herbs as Mahuang (Herba Ephedrae), Xixin (Herba Asari), Gansui (Radix Euphorbine Kansui), etc were processed into drug paste to be applied to the acupoints about 3～4 hr for adults and 1～2 hr for children, once in the first, the middle and the last of the three ten day periods of the hot season. In acupuncture group, these acupoints were punctured once every other day, beginning from the first day of the three ten day periods of the hot season on to the end of the hot season. Plasma SP and VIP were detected with radioimmunoassay. Results: After treatment, in MV group, 6 cases were under control, 9 had marked improvement, 8 had improvement and 4 had no effect, with an effective rate of 85.2%. In acupuncture group, 3 cases were under control, 8 and 8 had marked improvement and improvement respectively, and 6 had no effect, with an effective rate of 76%. Plasma SP level increased significantly and VIP decreased considerably in comparison with pre treatment in these two groups(P<0.05). Conclusion: Both MV and acupuncture can effectively improve asthma patients' symptoms, lower plasma SP and raise VIP level significantly.