中医慢病护理管理对缓解慢性乙型肝炎患者的抑郁情绪及改善其治疗效果的影响

目的:探讨中医慢病护理管理在缓解慢性乙型肝炎(Chronic Hepatitis B,CHB)患者的抑郁情绪及改善其治疗效果的影响。方法:选择2017年2月-8月至我院进行治疗的慢性乙型肝炎患者60例作为研究对象,通过不同护理模式分为实验组29例,对照组31例,对照组运用常规护理,实验组运用中医慢病护理管理。比较两组患者的实验室相关检测指标、中医临床证候量表评分、抑郁情绪及生活质量。结果:实验组患者干预后谷丙转氨酶(Alanine Aminotransferase,ALT)复常率明显低于对照组(P<0.05),乙型肝炎E抗原(Hepatitis Be Antigen,HBeAg)血清学转换率及乙肝病毒的脱氧核糖核酸(HBV-DNA)阴转率两组差异无统计学意义(P>0.05)。干预后,两组患者中医临床证候量表各维度评分均较干预前均显著下降,且实验组评分显著低于对照组(P<0.05)。干预后,两组抑郁评分较干预前均明显下降,且实验组显著低于对照组(P<0.05)。干预前两组患者生活质量各维度评分差异无统计学意义(P>0.05),干预后实验组患者生理职能(Role Limitation because of Physicai Problem,RP)、社会功能(Social Function,SF)、情感智能(Role Limitation because by Emotional Problem,RE)、心理健康(Mental Health,MH)评分均显著高于对照组(P<0.05),且实验组生活质量总分(545.43±53.86)分显著高于对照组(488.87±53.62)分(t=4.074,P<0.05)。结论:中医慢病护理管理有助于提高慢性乙型肝炎患者的治疗效果,缓解抑郁情绪,促进肝功能恢复,改善患者症状,提高其生活质量,值得临床推广应用。

Efficacy of TCM chronic care management on depressive mood and CHB

Objective:To explore the effect of TCM chronic care management on depressive mood and CHB.Methods:60 patients with chronic hepatitis B were divided into the experimental group and control group,31 cases in each.The control group is applied routine nursing and the experimental group is applied TCM chronic care management.The laboratory-related test indicators,TCM clinical symptom scale score,depression mood and quality of life were compared between the two groups.Results:The ALT recurrence rate in the experimental group was significantly lower than that in the control group(P<0.05).There was no significant difference between the HBeAg seroconversion rate and the HBV-DNA negative conversion rate after the intervention(P>0.05).After the intervention,the scores of the TCM clinical symptom scales in the two groups were significantly lower than those before the intervention,and the scores in the experimental group were significantly lower than the control group(P<0.05).After the intervention,the depression scores in two groups were significantly lower than those before the intervention,and those in the experimental group were significantly lower than the control group(P<0.05).There was no significant difference in the scores of quality of life between the two groups before intervention(P>0.05).After the intervention,the scores of RP,SF,RE and MH in the experimental group were significantly higher than those in the control group(P<0.05).The total mass score(545.43±53.86)was significantly higher than(488.87±53.62)in the control group(t=4.074,P<0.05).Conclusion:TCM chronic care management can improve the therapeutic effect,relieve depression and promote liver function recovery as well as improve patient symptoms and their quality of life.It is worthy of clinical application.