| 缩泉丸治疗氯氮平所致流涎的临床观察 |
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| 引用本文： | 康冰,刘玉成,张雅萍,韩玉,樊禄珍,周军.缩泉丸治疗氯氮平所致流涎的临床观察[J].中国中西医结合杂志,1993,13(6):347-348,325. |
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| 作者姓名： | 康冰 刘玉成 张雅萍 韩玉 樊禄珍 周军 |
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| 作者单位： | 南京神经精神病防治院，南京神经精神病防治院，南京神经精神病防治院，南京神经精神病防治院，南京神经精神病防治院，南京神经精神病防治院 江苏 210029，江苏 210029，江苏 210029，江苏 210029，江苏 210029，江苏 210029 |
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| 摘 要： | 采用双盲法观察缩泉丸治疗氯氮平所致流涎的疗效。缩泉丸治疗组21例,治疗后流涎症状较19例对照组明显减少(P<0.01)。中医辨证分型与缩泉丸治疗关系分析,表明痰湿内阻型和阳虚亏损型疗效最佳。氯氮平血浓度与流涎两者间无相关性(P>0.05)。
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| 关 键 词： | 缩泉丸 氯氮平 流涎 |
Clinical Observation on Effect of Suo Quan Pill for Reducing Clozapine Induced Salivation |
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| Authors: | Kang Bing |
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| Abstract: | 40 Schizophrenic inpatients with clozapine induced salivation were divided into two groupsrandomly. They were treated with Suo Quan pill and a control study of the placebo (neutral pill) forreducing clozapine induced salivation. These cases were also classified by TCM Syndrome Differen-tiation and laboratory examinations were performed. Results: There was a significant difference ineffect on salivation between the therapeutic group (21 cases) and the controlled group (19 cases), P<0.01. According to their TCM subtypes two subtypes (Stagnation of Phlegm-Dampness and YinDeficiency) showed the best results. No correlation between the peripheral clozapine level andsalivation was found. No side effect was recorded. |
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| Keywords: | Suo Quan Pill clozapine salivation |
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