The Role of Resveratrol Administration in Human Obesity |
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| Authors: | Laura M. Mongioì ,Sandro La Vignera,Rossella Cannarella,Laura Cimino,Michele Compagnone,Rosita A. Condorelli,Aldo E. Calogero |
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| Affiliation: | Department of Clinical and Experimental Medicine, University of Catania, Policlinico “G. Rodolico”, Via S. Sofia 78, 95123 Catania, Italy; (L.M.M.); (S.L.V.); (R.C.); (L.C.); (M.C.); (R.A.C.) |
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| Abstract: | Obesity is a widespread disease that is associated with numerous and serious comorbidities. These include metabolic syndrome, diabetes mellitus, cardiovascular-cerebrovascular disease, hypertension, obstructive sleep apnea syndrome, cancer, and sexual and hormonal disorders. The treatment of obesity has therefore become a goal of great clinical and social relevance. Among the therapeutic strategies against obesity, resveratrol has aroused great interest. This polyphenol has anticancer and antioxidant properties and cytoprotective and anti-inflammatory effects. Other favorable effects attributed to resveratrol are anti-lipid, anti-aging, anti-bacterial, anti-viral, and neuroprotective actions. Administration of resveratrol appears to improve the metabolic profile in obese and/or insulin-resistant patients. This article aims to review the main results of clinical studies evaluating the effects of administering resveratrol alone in overweight/obese patients. |
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| Keywords: | resveratrol obesity clinical trials |
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