高乌甲素治疗56例胆道术后病人疼痛的临床疗效分析

目的：观察高乌甲素在胆道手术后的镇痛效果。方法：选择本院2007年1月至2008年1月择期行胆道手术患者56例,随机分为高乌甲素组和芬太尼组,分别在手术后给予高乌甲素和芬太尼进行术后镇痛。结果：胆道手术术后48h内高乌甲素组和芬太尼组的临床治疗效果没有显著的统计学差异（P〉0.05）,且高乌甲素组比芬太尼组在恶心、呕吐、嗜睡、皮肤瘙痒等副反应上要小得多（P〈0.01）。结论：应用高乌甲素对胆道手术术后镇痛有良好效果,与芬太尼的镇痛效果相当,但高乌甲素副作用要小得多,术后患者的接受度更佳,适宜临床推广使用。

Clinical analgesic effect of lappaconitine in 56 patients after cholecystectomy

AIM：To study the analgesic effect of lappaconitine in patients after cholecystecystectomy. METHODS：Fifty-six patients aging 20-65 were randomly divided into two groups （28 patients per group）. Lappaconitine group received lappaconitine 40 mg and Fentanyl group fentanyl 0.4 mg. RESULTS：Compared with Lappaconitine group,the pain scaling of patients who received lappaconitine were similar to fentanyl （P〉0.05）,but there were significant differences on the side-effects such as itch of skin,nausea and vomiting between two groups （P〈0.01）. CONCLUSION：Compared with Lappaconitine group,the pain feel of the patients who received fentanyl were equal,but the side effects such as itch of skin,nausea and vomiting in Lappaconitine group were less.