非淋菌性尿道炎女性解脲支原体感染情况及药敏趋势分析

目的:了解2009～2011年威海地区解脲支原体引起的女性非淋菌性尿道炎感染现状及其药物敏感情况,为生殖道支原体感染的防治提供科学依据。方法:采用支原体培养、鉴定及药敏一体化试剂盒对女性生殖道感染患者进行检测。用SPSS11.0统计软件包进行统计学分析。结果:1288例疑似支原体感染的女性中,单纯解脲支原体阳性604例,检出率为46.89%。药敏试验结果显示,解脲支原体对8种抗生素的敏感性从高到低分别为交沙霉素(99.34%)、强力霉素(98.68%)、四环素(96.03%)、克拉霉素(92.55%)、阿奇霉素(79.80%)、红霉素(79.47%)、氧氟沙星(18.38%)、环丙沙星(9.44%)。结论:解脲支原体感染率3年来并无变化,同时对应的药物敏感性也无变化。交沙霉素和强力霉素可作为首选用药。但对支原体感染的治疗,仍要根据药物敏试验结果合理选用抗生素,降低耐药菌株的产生。

Prevalence and drug Resistance of ureaplasma urealyticum in female patients with non-gonococcal urethritis

Objective: To investigate the status of female patients with genitourinary tract infection caused by Ureaplasma urealyticum(Uu) and its drag susceptibility in Weihai to provide guidance for rational clinical treatment. Methods: The secretion specimen collected from female patients with the non-gonoccocal urethritis(NGU) was tested by mycoplasma cultivation, identification and drug susceptibility integration kit. The data were statistically analyzed with SPSS11.0. Results: The positive rates of Uu in 1288 suspicious NGU female patients were 54.04%. during 2009-2012. Antibiotics susceptibility was as followed: JOS 99.34%、DOX98.68%、 TE96.03%、CLA92.55%、AZI79.80%、ROX79.47%、OFL18.38%、CIP9.44%. Conclusion:The infection rate of Uu in female of the local region was no change during 2009-2011, and there was no significant difference of Uu susceptibility to antibiotics. Josamycin and doxycycline should be the first choices for the treatment of ureaplasma urealyticum infection.But the doctor should rationally choose antibiotics according to the drug susceptibility for avoiding the produce of drug-resistance mycoplasma individual.