| 注射用重组改构人肿瘤坏死因子治疗恶性胸腔积液临床观察 |
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| 引用本文： | 汪舸,闵海燕,张航. 注射用重组改构人肿瘤坏死因子治疗恶性胸腔积液临床观察[J]. 现代肿瘤医学, 2011, 19(10): 2029-2030. DOI: 10.3969/j.issn.1672-4992.2011.10.39 |
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| 作者姓名： | 汪舸 闵海燕 张航 |
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| 作者单位： | 南京医科大学附属常州市第二人民医院肿瘤科,江苏,常州,213002 |
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| 摘 要： | 目的:探讨注射用重组改构人肿瘤坏死因子(recombinant metant human tumor necrossis factor,rmhT-NF)和顺铂(cisplatin,DDP)治疗恶性胸水的疗效和不良反应。方法:将60例恶性胸水患者随机分为rmhTNF组和DDP组,观察各组的疗效、起效时间和副反应。结果:TNF组总有效率86.7%,DDP组总有效率66.7%,TNF组效果好于DDP组,P<0.05,有统计学意义。结论:使用rmhTNF治疗恶性胸水起效较快,疗效确切,较顺铂治疗副反应小,操作简便,有临床应用价值。
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| 关 键 词： | 恶性胸腔积液 注射用重组改构人肿瘤坏死因子 顺铂 |
A clinical observation of malignant pleural effusion treated by intrapleural perfusion with recombinant mutant human tumor necrosis factor |
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| WANG Ge,MIN Haiyan,ZHANG Hang. A clinical observation of malignant pleural effusion treated by intrapleural perfusion with recombinant mutant human tumor necrosis factor[J]. Journal of Modern Oncology, 2011, 19(10): 2029-2030. DOI: 10.3969/j.issn.1672-4992.2011.10.39 |
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| Authors: | WANG Ge MIN Haiyan ZHANG Hang |
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| Affiliation: | WANG Ge,MIN Haiyan,ZHANG Hang Department of Oncology,the Affiliated Hospital of Nanjing Medical University,Jiangsu Changzhou 213002,China. |
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| Abstract: | Objective:To approach the clinical effect and adverse reaction of recombinant metant human tumor necrossis factor(rmhTNF) and DDP in the treatment of malignant pleural effusion.Methods: Sixty patients with maligant pleural effusion were randomly devided into two groups:groupTNF was infused with rmhTNF,the another one was infused with DDP.The effective rate,responding time and adverse reaction were observed.Results: The total effective rate of rmhTNF group was 86.7%,while it was 66.7% in groupDDP.There was a... |
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| Keywords: | malignant pleural effusion rmhTNF DDP |
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