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肾移植术后排斥反应与巨细胞病毒感染有关
引用本文:张泓,武大林,吴涛,籍会彩.肾移植术后排斥反应与巨细胞病毒感染有关[J].中国现代医学杂志,2002,12(2):21-22.
作者姓名:张泓  武大林  吴涛  籍会彩
作者单位:第一军医大学附属南方医院外科实验室,广州,510515
摘    要:目的 :探讨巨细胞病毒 (CMV)感染在肾移植术后的发生率及CMV感染与排斥反应的关系。方法 :检测2 0 8例肾移植受者术后CMVDNA和 48例肾移植受者血清CMVIgM、IgG抗体。并定期复查CMVDNA ,对CMVDNA阳性的患者给予抗病毒治疗。结果 :术后CMVDNA阳性受者急性排斥反应的发生率增加 ,经抗CMV治疗 ,则排斥反应减少。结论 :预防和治疗CMV感染的重要性

关 键 词:巨细胞病毒感染  肾移植  移植物排斥
修稿时间:2001年12月29

CYTOMEGALOVIRUS INFECTION IS RELATED TO THE REJECTION IN RENAL ALLOGRAFT RECIPIENTS
Zhang Hong,Wu Dalin,Wu Tao,et al..CYTOMEGALOVIRUS INFECTION IS RELATED TO THE REJECTION IN RENAL ALLOGRAFT RECIPIENTS[J].China Journal of Modern Medicine,2002,12(2):21-22.
Authors:Zhang Hong  Wu Dalin  Wu Tao  
Affiliation:Zhang Hong,Wu Dalin,Wu Tao,et al. The First Military Medical University,Guangzhou 510515
Abstract:Objective:To investigate the incidence of cytomegalovirus (CMV) infection in renal allograft recipients and the impact of CMV infection on rejection.Methods:207 renal allograft recipients were subjected to the PCR for CMV DNA after transplantation,48 recipients were subjected to the serum test for CMV- antibody IgM and IgG. CMV-DNA in recipients were detected in certain time. The patients with positive CMV DNA were given anti-CMV treatment.Results:CMV DNA( ) in recipients after operation enhanced the development of rejection. Ganciclovir therapy reduced the incidence of rejection.Conclusion:It is important to prevent and treat CMV infection in renal allograft recipients.
Keywords:Cytomegalovirus Infection  Kidney Transplantation  Graft Rejection
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