染色内镜和放大内镜技术是提高早期大肠癌诊治水平的重要手段

应用常规内镜技术难以发现大肠平坦型病变和凹陷型病变。近年来染色内镜和放大内镜技术已经发展成熟,在国外已获广泛应用,可以发现大肠微小病变和早期大肠癌。应用腺管开口分型方法可以预测肿瘤病变的组织学类型及肿瘤的浸润深度,据此可确定行内镜下粘膜剥离术或分片粘膜剥离术将肿瘤切除,抑或行外科手术治疗。在当前我国的胃肠内镜医疗界,应广泛开展染色内镜和放大内镜的临床应用,以早期发现大肠病变,提高我国大肠癌的内镜诊治水平。

Chromoendoscopy and high-magnification colonoscopy in early detection of colorectal cancer

Flat and depressed lesions in the colons are difficult to detect with conventional colonoscopic techniques, and chro-moendoscopy with high magnification has consequently gaincd wide application for early detection of colorectal cancer andits precursors. These techniques allow targeted in vivo luminal treamients and make possible earier and more accurate diagno-sis on the basis of pit pattem classification as proposed by Kudo Sinei. According to studies conducted by Japanese re-searchers, magnification chromoendoscopy can be used to assess the histology and invasive depth of the cancer, and thus helpin the detection of flat and depressed cokonic lesions and the subsequent surgical treatment of these lesions by way of endo-scopic mucosal resection (EMR) or endoscopic piecemeal mucosal resection (EPMR). Due attention should be given to theclinical significance of high-magnification chromoendoscopy in the identification of the lesions.