车间空气中玻璃钢粉尘卫生标准研制

目的　制订车间空气中玻璃钢粉尘卫生标准。方法　采用现场劳动卫生流行病学调查方法及用玻璃钢粉尘对大鼠肺脏进行致纤维化实验研究 ,观察大鼠全肺干质量和全肺胶原蛋白含量。结果　该粉尘可引起大鼠全肺干质量和全肺胶原蛋白含量增加 (P <0 0 1或P <0 0 5 ) ,且有剂量 反应关系 ,作业工人有“尘肺”样改变。结论　根据动物实验研究和现场劳动卫生学调查结果 ,提出车间空气中玻璃钢粉尘最高容许浓度为 6mg/m3,时间加权平均容许浓度为 3mg/m3。

Preparation for the health standard of fiberglass reinforced plastic dust

Objective To workout the health standard of fiberglass reinforced plastic dust in the air of workplace.Method Occupational epidemiological investigation on field workers was performed, the dry weight of lungs and the content of collagenous protein in lungs of the fiberglass reinforced plastic dust exposed rats were observed,too.Results The dust could cause the dry weight of lungs and the content of collagenous protein in lungs of the exposed rats increase(P<0 05 or P<0 01)and showed dose response relationship.The dust exposed workers also had the changes of pneumoconiosis.Conclusion It is suggested that the MAC of 6 mg/m 3 and TWA of 3mg/m 3 of the fiberglass reinforced plastic dust in the air of workplace seems adequate and safe.