| 蓝玉簪龙胆提取液抗呼吸道合胞病毒的初步实验研究 |
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| 引用本文： | 卫飞鹏,田琼,李晓冰,郭卫平,李旭波,刘菁菁,陈娟娟. 蓝玉簪龙胆提取液抗呼吸道合胞病毒的初步实验研究[J]. 儿科药学杂志, 2011, 17(2): 4-7 |
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| 作者姓名： | 卫飞鹏 田琼 李晓冰 郭卫平 李旭波 刘菁菁 陈娟娟 |
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| 作者单位： | 卫飞鹏,李晓冰,郭卫平,Wei Feipeng,Li Xiaobing,Guo Weiping(第四军医大学唐都医院,陕西西安,710038);田琼,李旭波,刘菁菁,陈娟娟,Tian Qiong,Li Xubo,Liu Jingjing,Chen Juanjuan(第四军医大学药学系,陕西西安,710032) |
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| 基金项目： | 中国人民解放军军队"十一五"课题 |
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| 摘 要： | 目的:观察蓝玉簪龙胆水煎液及正丁醇、乙酸乙酯、氯仿提取液在体内外的抗呼吸道合胞病毒(RSV)作用.方法:通过观察细胞病变效应(CPE)和MTT比色,评价不同浓度的蓝玉簪龙胆提取液抑制RSV感染HEP-2细胞的病变作用;通过HE染色和免疫荧光染色,评价蓝玉簪龙胆水煎液对RSV感染小鼠肺组织炎性病变抑制效果.结果:体外实验...
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| 关 键 词： | 蓝玉簪龙胆 呼吸道合胞病毒 抗病毒 体内 体外 |
Empirical Study of Anti-RSV Effect on Gentiana Veitchiorum |
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| Wei Feipeng,Tian Qiong,Li Xiaobing,Guo Weiping,Li Xubo,Liu Jingjing,Chen Juanjuan. Empirical Study of Anti-RSV Effect on Gentiana Veitchiorum[J]. Journal of Pediatric Pharmacy, 2011, 17(2): 4-7 |
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| Authors: | Wei Feipeng Tian Qiong Li Xiaobing Guo Weiping Li Xubo Liu Jingjing Chen Juanjuan |
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| Affiliation: | Wei Feipeng,Tian Qiong,Li Xiaobing,Guo Weiping,Li Xubo,Liu Jingjing,Chen Juanjuan (1.Tangdu Hospital,The Fourth Military Medical University,Shanxi Xi'an 710038,China,2.The Fourth Military University,Shanxi Xi'an 710032,China) |
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| Abstract: | Objective: To observe the anti-RSV effect of Gentiana veitchiorum decoction,n-butanol extract,ethyl acetate extract,chloroform extract in vitro and vivo.Methods: To observe cytopathic effect(CPE) and Methyl thiazolyl tetrazolium(MTT) assay,the effect of anti-RSV was evaluated with RSV infected hep-2 cells for different Gentiana veitchiorum.The degree of mouse lung tissue inflammation was evaluated by experimental hematoxylin and eosin(HE) staining and immunofluorescence.Results: After the different Gentiana... |
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| Keywords: | Gentiana veitchiorum RSV Antiviral In vitro In vivo |
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