| 2-羟基咔唑的合成与表征 |
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| 引用本文： | 周铎,杨振强,陈辉,王朝杰,杨瑞娜.2-羟基咔唑的合成与表征[J].河南师范大学学报(自然科学版),2015(2):84-86. |
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| 作者姓名： | 周铎 杨振强 陈辉 王朝杰 杨瑞娜 |
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| 作者单位： | 河南省科学院化学研究所有限公司;濮阳惠成电子材料股份有限公司 |
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| 基金项目： | 河南省科技成果转化项目(142201210046);郑州市重点攻关项目(141PZDGG218) |
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| 摘 要： | 以邻溴硝基苯为起始原料,依次与双(频那醇合)二硼,对溴苯甲醚经Suzuki-Miyaura反应合成了2-硝基-4’-甲氧基联苯,然后经亚磷酸三乙酯还原反应,三溴化硼催化脱甲基化合成了目标产物2-羟基咔唑,总收率68.9%.通过1 HNMR、13 C NMR表征了合成化合物结构.
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| 关 键 词： | 2-羟基咔唑 2-甲氧基咔唑 合成 表征 |
Synthesis and Characterization of 2-Hydroxycarbazole |
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| ZHOU Duo;YANG Zhenqiang;CHEN Hui;WANG Chaojie;YANG Ruina.Synthesis and Characterization of 2-Hydroxycarbazole[J].Journal of Henan Normal University(Natural Science),2015(2):84-86. |
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| Authors: | ZHOU Duo;YANG Zhenqiang;CHEN Hui;WANG Chaojie;YANG Ruina |
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| Affiliation: | ZHOU Duo;YANG Zhenqiang;CHEN Hui;WANG Chaojie;YANG Ruina;Institute of Chemistry Henan Academy of Sciences Co.,Ltd;Puyang Huicheng Electronic Material Co.Ltd; |
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| Abstract: | 2-nitro-4'-methoxy-biphenyl was synthesized with 2-bromonitrobenzene as the starting material,sequentially reacting with bis(pinacolato)diboron and 4-bromoanisole via Suzuki-Miyaura reaction.Then this compound was reduced with triethylphosphite,followed by demethylation with BBr3 to synthesize the target product 2-hydroxycarbazole with the total yield of 68.9%.Synthetic compound was characterized by 1 HNMR and 13 C NMR. |
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| Keywords: | 2-hydroxycarbazole 2-methoxycarbazole synthesis characterization |
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