The analysis of thiodiglycollic acid by selected ion monitoring |
| |
| Authors: | B R Pettit |
| |
| Affiliation: | 1. ISGlobal, Doctor Aiguader, 88, Barcelona 08003, Spain;2. CIBER epidemiología y salud pública (CIBERESP), Av. Monforte de Lemos, 3-5, Madrid 28029, Spain;3. Universitat Pompeu Fabra (UPF), Doctor Aiguader 88, Barcelona 08003, Spain;4. IMIM (Hospital del Mar Medical Research Institute), Doctor Aiguader 88, Barcelona 08003, Spain;5. Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON K1A 0K9, Canada;6. Graduate School of Global Environmental Studies, Kyoto University, Rm252, Research Building 3, Yoshidahonmachi, Sakyo, Kyoto 606-8501, Japan;7. Department on Drinking Water Quality, Institute of Public Health of Serbia, Dr Subotica 5, Belgrade 11000, Serbia;8. Organic Chemistry Department, M.V. Lomonosov Moscow State University, Moscow 119991, Russia;9. Departamento de Ingeniería Civil y Ambiental, Universidad de los Andes, Cra. 1 Este #19a-40, Edificio Mario Laserna - Piso6 Bogotá, 111711, Colombia;10. Environmental Health Department, Institute of Public Health, Alexander Moisiu Nr. 80, Tirana, Albania;11. Divisão de Pneumologia, Instituto do Coração - InCor - Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 44, São Paulo (SP) 05403-900, Brazil;12. Departamento de Ingeniería Hidráulica y Ambiental, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna, Macul, Santiago 4860, Chile;13. Centro de Desarrollo Urbano Sustentable (CEDEUS), Av. Vicuña Mackenna, Macul, Santiago 4860, Chile;14. Quiñones Consulting, Colón 110-1301, Miraflores, Lima 15074, Peru;15. Office of Ground Water and Drinking Water, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave, N.W., Washington, DC 20460, USA;p. Department of Water Quality and Health Monitoring, National Institute of Environmental Health, China CDC, 29# Nanwei Road, Xicheng District, Beijing 100050, PR China;q. Department of Preventive Medicine, Dankook University College of Medicine, 119 Dandae-ro Cheonan-si, Chungnam-do 31116, South Korea;r. Department of Environmental Engineering, King Mongkut''s University of Technology Thonburi, 126 Pracha-Utit Rd., Bangmod, Tungkru, Bangkok 10140 Thailand;s. Eawag, Swiss Federal Institute of Aquatic Science and Technology, Duebendorf CH-8600, Switzerland;t. Ahmadu Bello University, Samaru Campus, Zaria, Kaduna State, Nigeria;u. Research Centre for Hauora and Health, Massey University, Wellington Campus, PO Box 756, Wellington 6140, New Zealand;v. Norwegian Institute of Public Health, P.O. Box 4404 Nydalen, Oslo NO-0456, Norway;w. Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC 29208, USA;x. Department of Civil and Environmental Engineering, University of Massachusetts, Amherst, MA 01062, USA;y. Metropolitan Water District of Southern California, Water Quality Laboratory, 700 Moreno Ave La Verne, California 91750, USA;z. MRC Centre for Environment and Health, School of Public Health, Imperial College London, Michael Uren Biomedical Engineering Hub, White City Campus, Wood Lane, London W12 0BZ, UK;1. Department of Environmental Toxicology, Faculty of Health Sciences, Medical University of Gdansk, Dębowa Str. 23A, 80-204 Gdansk, Poland;2. Department of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury, Oczapowskiego Str. 1A, 10-719 Olsztyn, Poland;3. Department of Soil Science Erosion and Land Protection, Institute of Soil Science and Plant Cultivation - State Research Institute, Czartoryskich Str. 8, 24-100 Puławy, Poland;4. Laboratory of Biohazards, Department of Chemical, Aerosol and Biological Hazards, Central Institute for Labour Protection – National Research Institute, Czerniakowska Str. 16, 00-701 Warsaw, Poland;5. Department of Microbiology, Faculty of Medicine, Medical University of Gdansk, Dębowa Str. 25, 80-204 Gdansk, Poland |
| |
| Abstract: | A selected ion monitoring assay for thiodiglycollic acid in urine is described. Urine samples are analysed by combined gas chromatography-mass spectrometry as their dibutyl esters using pimelic acid as an internal standard. Rapid analysis was achieved by the simplification of sample preparation. The assay has proved to be reliable, with a detection limit of less than 0.5 mumol/l. The excretion of large amounts of thiodiglycollic acid in premature babies urine has been confirmed, with the greatest excretion occurring from those neonates born with a gestational age of 30 wk or less. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
