改良羊膜移植在预防和治疗外伤性角膜穿孔中的应用

目的:探讨生物胶粘贴缝合双层羊膜遮盖防治外伤性角膜穿孔的可行性。方法:15例18眼角膜损伤患者实施双层羊膜移植,其中角膜穿孔者14眼,深层溃疡达角膜1/3基质以上者4眼。小片羊膜覆盖在溃疡或穿孔处,将生物胶滴于羊膜、角膜表面,并将大片羊膜迅速贴于角膜表面。10/0尼龙线间断缝合大片羊膜于结膜创缘及浅层巩膜上。结果:所有患者视力均优于术前。术中及术后未见特殊并发症。结论:双层羊膜粘贴缝合治疗和预防外伤性角膜穿孔,操作简单,效果显著。

Modified amniotic membrane overlay transplantation for preventing and treating traumatic cornea perforation

AIM:To study the feasibility of biological adhesive in fixation of two-layer amniotic membrane transplantation(AMT) for preventing and treating traumatic cornea perforation. ·METHODS: Two-layer AMT was performed on 15 patients(18 eyes) with corneal injury,14 eyes with traumatic cornea perforation,and 4 eyes with severe corneal ulcer upward of 1/3 corneal matrix. A small piece of amniotic membrane was covered on the focus,and a large one on the whole cornea by biological adhesive. The large amniotic membrane was sutured interruptedly to the traumatic edge of conjunctiva and superficial sclera by 10/0 nylon suture line. ·RESULTS: Vision of all patients was improved. No specific complications were found in the operation and after operation. ·CONCLUSION: Two-layer AMT by biological adhesive is a very effective method to treat and prevent traumatic cornea perforation,and operation is simple.