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鼻泪管黏膜相关淋巴组织形态学分析
引用本文:张涛,王继群,王丽华,山艳春. 鼻泪管黏膜相关淋巴组织形态学分析[J]. 临床耳鼻咽喉头颈外科杂志, 2004, 18(8): 488-489
作者姓名:张涛  王继群  王丽华  山艳春
作者单位:暨南大学附属第一医院耳鼻咽喉科,广州,510632;暨南大学附属第一医院耳鼻咽喉科,广州,510632;暨南大学附属第一医院耳鼻咽喉科,广州,510632;暨南大学附属第一医院耳鼻咽喉科,广州,510632
基金项目:广东省医学科研基金资助项目 (No :A2 0 0 4 35 5 ),暨南大学医学院科研基金资助项目 (No :2 0 0 30 8)
摘    要:目的 :探讨鼻泪管黏膜相关淋巴组织的组织学特点 ,初步揭示泪道炎症不易治愈的局部原因。方法 :通过常规苏木精 伊红染色 ,利用图像分析仪对兔鼻泪管、鼻腔、咽腔和气管黏膜中的淋巴滤泡发育情况 ,高内皮静脉 (HEV)的分布情况及其周围淋巴细胞浸润的密度进行分析。结果 :鼻泪管黏膜组织中淋巴滤泡和HEV的数量及其周围淋巴细胞浸润的程度均低于鼻腔、咽腔和气管黏膜 (P <0 .0 1)。结论 :正常情况下鼻泪管黏膜的局部免疫反应程度低于鼻腔、咽腔和气管黏膜 ,其黏膜下淋巴组织欠发达可能是泪道炎症不易治愈的主要原因。

关 键 词:鼻泪管  黏膜相关淋巴组织  组织学
文章编号:1001-1781(2004)08-0488-02
修稿时间:2003-12-25

Morphologic study of nasolacrimal duct mucosa-associated lymphoid tissue
ZHANG Tao WANG Jiqun WANG Lihua SHAN Yanchun. Morphologic study of nasolacrimal duct mucosa-associated lymphoid tissue[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2004, 18(8): 488-489
Authors:ZHANG Tao WANG Jiqun WANG Lihua SHAN Yanchun
Affiliation:Department of Otorhinolaryngology, the First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Abstract:Objective:To investigate the features of nasolacrimal duct MALT (mucosa-associated lymphoid tissue), and to explore the aetiology of chronic dacryocystitis.Method:The mucous of nasolacrimal duct, nasal cavity, pharyngeal and trachea of 20 rabbits were studied, and the lymphoid tissue and HEV of them were compared.Result:The number of lymphoid follicle and HEV in nasolacrimal duct epidermis were less than that in nasal cavity, pharyngeal and trachea(P< 0.01 ).Conclusion:In normal condition the immune response of nasalacrimal duct membranae is lower than other mucosa of head-neck.
Keywords:Nasolacrimal duct  Mucosa-associated lymphoid tissue  Histology
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