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黄芩茎叶总黄酮抗心肌缺血作用
摘    要:黄芩茎叶总黄酮是黄芩茎叶的主要有效部位,以总黄酮100mg.kg-1、500ng.kg-1、25mg.kg-1po给药,可明显延长小鼠常压缺氧的存活时间,对iv垂体后叶素引起的大鼠心肌缺血有明显的对抗作用,并可增加离体豚鼠的冠脉流量

关 键 词:黄苓茎叶 总黄酮 心肌缺血 药理

MYOCARDIAL ISCHEMIA RESISTING EFFECT OF TOTAL FLAVONOID FROM STEMS AND LEAVES OF SCUTELLARIA BAICALENSIS
Tong Jiming et al Institute of Chinese materia medica. MYOCARDIAL ISCHEMIA RESISTING EFFECT OF TOTAL FLAVONOID FROM STEMS AND LEAVES OF SCUTELLARIA BAICALENSIS[J]. Journal of Chengde Medical College, 1998, 15(4): 266-268
Authors:Tong Jiming et al Institute of Chinese materia medica
Affiliation:Tong Jiming et al Institute of Chinese materia medica
Abstract:Scutellaria baicalensis stem leaf total flavonoid (SSTF)is the main effective fragment of stems and leaves of Scutellaria baicalensis.It is respectively geven by po(100mg.kg -1 ,50mg.kg -1 ,and 25mg.kg -1 )to mice and rats.The experimental results showed SSTF can obviously prolongate the survival time in mice under anoxic condition at normal atmospheric pressure and resist myocardical ischemia induced by pituitrin in rats,and increase the coronary flow in isolated hearts from guinea pigs.
Keywords:Scutellaria baicalensis stem uleaf total fiavonoid (SSTF)  myocardical ischemia  
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