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Diversity‐Oriented Synthesis of Functionalized 1‐Aminopyrroles by Regioselective Zinc Chloride‐Catalyzed,One‐Pot ‘Conjugate Addition/Cyclization’ Reactions of 1,3‐Bis(silyl enol ethers) with 1,2‐Diaza‐1,3‐butadienes |
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| Authors: | Vahuni Karapetyan Satenik Mkrtchyan Andreas Schmidt Orazio&#x;A Attanasi Gianfranco Favi Fabio Mantellini Alexander Villinger Christine Fischer Peter Langer |
| Abstract: | In a convenient one‐pot process, the easily accessible 1,2‐diaza‐1,3‐butadienes and 1,3‐bis(silyl enol ethers) are converted into the previously unknown functionalized 1‐aminopyrroles and 1‐amino‐4,5,6,7‐tetrahydroindoles. The domino reaction proceeds through a zinc chloride‐catalyzed ‘conjugate addition/cyclization’ sequence. |
| Keywords: | cyclizations 1 2‐diaza‐1 3‐butadienes N‐heterocycles pyrroles silyl enol ethers |
