| 感染患者血清可溶性细胞间粘附分子含量的变化及其对脑梗死的影响 |
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| 引用本文： | 王洪新,杨忠,鹿树军,周晓生,衣香明,郑麒.感染患者血清可溶性细胞间粘附分子含量的变化及其对脑梗死的影响[J].滨州医学院学报,2002,25(2):102-104. |
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| 作者姓名： | 王洪新 杨忠 鹿树军 周晓生 衣香明 郑麒 |
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| 作者单位： | 滨州医学院附属医院神经内科,滨州市,256603 |
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| 摘 要： | 目的：探讨感染合并脑梗死患者血清可溶性细胞间粘附分子（sICAM-1)的变化及临床意义。方法：采用双抗体（ELISA）法测定50例感染合并脑梗死患者血清中sICAM-1的含量，并与30例脑梗死患者和30例健康人对照。结果：感染合并脑梗死患者急性期血清sICAM-1的水平明显高于对照组。结论：感染合并脑梗死时sICAM-1的表达明显升高，sICAM-1水平的增高加重了脑梗死的发生发展。
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| 关 键 词： | 脑梗死 可溶性细胞间粘附分子 感染 |
| 文章编号： | 1001-9510(2002)02-0102-03 |
| 修稿时间： | 2001年10月20日 |
THE CHANGE OF SERUM SICAM-1 LEVEL IN PATIENTS WITH INFECTION AND ITS EFFECT ON CEREBRAL INFARCTION |
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| Wang Hongxin,Yang Zhong,Lu Shujun,et al.THE CHANGE OF SERUM SICAM-1 LEVEL IN PATIENTS WITH INFECTION AND ITS EFFECT ON CEREBRAL INFARCTION[J].Journal of Binzhou Medical College,2002,25(2):102-104. |
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| Authors: | Wang Hongxin Yang Zhong Lu Shujun |
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| Abstract: | Objective:To explore the change of soluble intercellular adhesion molecule(sICAM 1) concentration in serum of patients with infection complicated by cerebral infarction and its clinical significance.Methods:In 50 patients with infections complicated by acute cerebral infarction,30 normal subjects,and 30 patients with acute cerebral infarction,the level of serum sICAM 1 was measured by two layer antibody sandwich enzyme linked immunosorbent assay.Results:The level of serum sICAM 1 in patients with infection complicated by cerebral infarction was higher than that in controls ( P <0 01).Conclusion:In the patients with infection complicated by acute cerebral infarction,there was an obvious increase of serum sICAM 1 level,which in turn accelerated the development and production of cerebral infarction. |
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| Keywords: | infection sICAM 1 cerebral infarction |
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