终末期肾脏病血液透析患者QT间期离散度与室性心律失常的关系研究

目的检测50例终末期肾脏病行维持性血液透析(MHD)患者透析前后体表心电图QT间期离散度(QTd)的变化,并初步探讨MHD患者QTd与室性心律失常的关系。方法 50例MHD患者分别于透析前及透析后记录12导联同步心电图,计算QTd与QTcd值并观察室性心律失常的情况,进行统计学分析。结果 MHD患者透析后QTd及QTcd均较透析前明显增大(P<0.05);存在室性心律失常的MHD患透析前及透析后QTd、QTcd均高于无室性心律失常患者(P<0.05)。结论 MHD患者QT间期离散度在透析后明显增加,且与室性心律失常的发生有关,临床医师应重视对QT间期离散度的观测。

Correlation of QT Dispersion with Ventricular Arrhythmias in End Stage Renal Disease Patients with Maintenance Hemodialysis

Objective To investigate the change of QT dispersion （QTd） in 50 patients with end stage renal disease undergoing maintenance hemodialysis（MHD）,and therefore to study the relationship between QTd and ventricular arrhythmia in MHD patients. Methods 50 MHD patients were measured with 12-lead ECG before and after dialysis,then QTd and QTcd were calculated. Meanwhile, the ventricular arrhythmias were observation and statisitcal analysis were performed. Results Post- hemodialysis values of QTd and QTcd of MHD patients were larger than pre- hemodialysis values; QTd and QTcd before and after the hemodialysis in patients with ventricular arrhythmias were larger than patients without ventricular arrhythmia. Conclusion It is suggested that QTd level will increase after the procedure of dialysis in MHD patients, and might be related to the occurrence of ventricular arrhythmias. Clinicians should pay more attention to the QTd for MHD patients