| Synthesis and relaxivity of polycarboxylic hydrazone rare earth complexes——Relaxivity of α-oxo-pentanedioic acid benzoyl hydrazone Gd-complexes |
| |
| 摘 要： |
|
| 收稿时间： | 2000-02-14 |
Synthesis and relaxivity of polycarboxylic hydrazone rare earth complexes |
| |
| Zhengyin Yang,Fashen Li,Li Yang,Rudong Yang. Synthesis and relaxivity of polycarboxylic hydrazone rare earth complexes[J]. Chinese science bulletin, 2000, 45(20): 1844-1850. DOI: 10.1007/BF02886291 |
| |
| Authors: | Zhengyin Yang Fashen Li Li Yang Rudong Yang |
| |
| Affiliation: | (1) Chemistry and Engineering College, Lanzhou University, 730000 Lanzhou, China;(2) Department of Physics, Lanzhou University, 730000 Lanzhou, China;(3) National Laboratory of Applied Organic Chemistry, Lanzhou University, 730000 Lanzhou, China |
| |
| Abstract: | Synthesis of ligand, α-oxo-pentanedioic acid benzoyl hydrazone (H2LPB), and its six rare earth (La, Pr, Nd, Sm, Gd and Er) complexes are reported. The composition and the properties of the complexes were characterized by element analysis, thermal analysis, UV, IR and1H NMR spectra. Besides, relaxivity (R 1) of Gd-complex has been determined by INVREC.Au program, using inversion recovery pulse sequences, R1=8.05 mmol · L−1 · s−1. The acute toxicity of Gd-complex in animal has also been tested, and the median lethal dose (LD50) is equal to (468.2±30) mg/kg. |
| |
| Keywords: | α -oxo-pentanedioic acid benzoyl hydrazone rare earth complexes relaxivity |
| 本文献已被 SpringerLink 等数据库收录！ |
| 点击此处可从《科学通报(英文版)》浏览原始摘要信息 |
|
点击此处可从《科学通报(英文版)》下载全文 |
|
