重症监护病房临床分离病原菌分布及耐药性分析

目的 及时了解和动态掌握重症监护病房（ICU）病原菌分布及耐药趋势,指导临床合理使用抗菌药物.方法 对我院ICU 2007年-2009年所分离的病原菌的菌群分布及耐药性进行回顾性分析.结果 共分离出病原菌705株.其中革兰阴性菌占57.16%;革兰阳性菌占30.21%,真菌占12.62%.鲍曼不动杆菌和铜绿假单胞菌呈多重耐药.结论 非发酵菌已成为ICU感染的最常见病原菌,对常用抗生素耐药严重,应加强耐药监测,合理使用抗生素对有效控制ICU感染十分重要.

Analysis of the distribution and antibiotic resistance of pathogenic bacterial isolates from clinical specimens in intensive care unit

Objective To acquire the timely knowledge and dynamic information of the distribution of pathogenic bacteria and their trend in antibiotic resistance in intensive care unit （ICU） , and provide clinical guidance on rational use of antibiotics. Methods A retrospective analysis was conducted on the distribution of bacterial flora and drug resistance of microbial isolates from 2007 to 2009 in our ICU. Results A total of 705 strains of pathogenic bacteria were isolated： Gram -negative bacilli were 57.16 % ; Gram -positive cocci accounted for 30.21% and fungi comprised 12.62 % of the bacteria. Non - zymophytes were muhidrug resistant. Conclusion Acinetobacter baumannii and Pseudomonas aeruginosa are the most frequent pathogenic bacteria and are strongly resistant to common antibiotics. Drug resistance surveillance should be emphasized and rational use of antibiotics is of great importance to the effective control of infections in ICU.