| OBSERVATION OF THE EFFECTS OF LAK／IL－2 THERAPY COMBINIGN WITH LYCIUM BARBARUM POLYSACCHARIDES IN THE TREATMENT OF PATIENTS WI |
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| 引用本文： | 曹广文,杨文国,杜平,王雄彪. OBSERVATION OF THE EFFECTS OF LAK／IL－2 THERAPY COMBINIGN WITH LYCIUM BARBARUM POLYSACCHARIDES IN THE TREATMENT OF PATIENTS WI[J]. 中国癌症研究, 1995, 7(4): 293-297. DOI: 10.1007/BF02672797 |
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| 作者姓名： | 曹广文 杨文国 杜平 王雄彪 |
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| 作者单位： | Department of Microbiology . Second Military Medical Uiniversity，Shanghai 200433 |
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| 摘 要： | 曹广文，杨文国，杜平，王雄彪ＯＢＳＥＲＶＡＴＩＯＮＯＦＴＨＥＥＦＦＥＣＴＳＯＦＬＡＫ／ＩＬ－２ＴＨＥＲＡＰＹＣＯＭＢＩＮＩＧＮＷＩＴＨＬＹＣＩＵＭＢＡＲＢＡＲＵＭＰＯＬＹＳＡＣＣＨＡＲＩＤＥＳＩＮＴＨＥＴＲＥＡＴＭＥＮＴＯＦＰＡＴＩＥＮＴＳＷＩＴＨＡ...
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| 修稿时间： | 1995-09-17 |
Observation of the effects of LAK/IL-2 therapy combinign with lycium barbarum polysaccharides in the treatment of patients with advanced cancer (a report of 75 cases) |
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| Cao Guangwen,Yang Wenguo,Du Ping,Wang Xiongbiao. Observation of the effects of LAK/IL-2 therapy combinign with lycium barbarum polysaccharides in the treatment of patients with advanced cancer (a report of 75 cases)[J]. Chinese Journal of Cancer Research, 1995, 7(4): 293-297. DOI: 10.1007/BF02672797 |
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| Authors: | Cao Guangwen Yang Wenguo Du Ping Wang Xiongbiao |
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| Affiliation: | (1) Department of Microbiology, Second Military Medical University, 200433 Shanghai |
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| Abstract: | Senventy nine advanced cancer patients in a clinical trial were treated with LAK/IL-2 combining with Lycium Barbarum polysaccharides (LBP). Initial results of the treatment from 75 evaluable Patients indicated that objective ragression of cancer was achieved in Patients with malignant melanoma, renal cell carcinoma, colorectal carcinoma, lung caneer, nasophacyngeal carcinoma,malignant hydrothorax. The response rate of patients treated with LAK/IL-2 plus LBP was 40.9% while that of patients treated with LAK/IL-2 was 16.1% (P<0.05).The mean remission duration in Patients treated with LAK/IL-2 Plus LBP also lasted significantly longer.LAK/IL-2 plus LBP treatment led to more marked increase in NK and LAK cell activity than LAK/IL-2without LBP. The results indicated that LBP can be used as an adjuvant in the biotherapy of cancer. |
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| Keywords: | Lycium barbarum polysaccharides IL-2 LAK Malignant tumor. |
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