脑卒中病人睡眠-觉醒昼夜节律紊乱的影像学研究

目的探讨睡眠-觉醒昼夜节律紊乱脑卒中患者的脑结构改变,了解生物钟系统与其他脑组织之间可能的联系。方法收集存在睡眠-觉醒昼夜节律紊乱脑卒中患者(观察组)21例和无睡眠-觉醒昼夜节律紊乱脑卒中病人(对照组)92例影像学资料,比较两者之间的差别,寻找最可能引起睡眠-觉醒昼夜节律紊乱的脑区损害。结果通过比较发现,位于侧脑室枕角前部、丘脑外侧、岛叶后方、颞叶内侧的脑区脑组织损害可能与睡眠-觉醒昼夜节律紊乱有关。结论脑卒中病人中睡眠-觉醒昼夜节律紊乱的出现可能与特定的脑区损害有关。

Imaging study of sleep-wake circadian rhythm disorder in stroke patients

Objective To analysis the brain structural changes of sleep-wake circadian rhythm disorders in the stroke pa-tients,in order to understand the possible links between the circadian clock system and other brain tissue.Methods Retrospec-tive analysis of imaging data of stroke patients was performed,who were divided into study group composed of 21 cases with sleep-wake circadian rhythm disorders and the control group made up of 92 cases without this disorder,comparing the data be-tween two groups and finding the possible damaged brain areas causing this disorder.Result We found that the affected brain regions located in front of the lateral ventricle occipital horn,the lateral of the hypothalamus,the rear of the insular cortex,the medial of the temporal lobe may have some relationship with sleep-wake circadian rhythm disorders in the stroke patients.Con-clusion The sleep-wake circadian rhythm disorders in the stroke patients may be related to the specific damaged brain regions.