| 体外循环和非体外循环冠脉搭桥术对肾功能的影响 |
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| 引用本文： | 杜奇容,单根法,张辅贤,李小波,李国庆,钟立.体外循环和非体外循环冠脉搭桥术对肾功能的影响[J].上海交通大学学报(医学版),2003,23(2):162-164. |
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| 作者姓名： | 杜奇容 单根法 张辅贤 李小波 李国庆 钟立 |
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| 作者单位： | 上海第二医科大学新华医院胸心外科，上海第二医科大学新华医院胸心外科，上海第二医科大学新华医院胸心外科，上海第二医科大学新华医院胸心外科，上海第二医科大学新华医院胸心外科，上海第二医科大学新华医院胸心外科 上海 200092，上海 200092，上海 200092，上海 200092，上海 200092，上海 200092 |
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| 摘 要： | 目的：研究体外循环和非体外循环冠脉搭桥术对肾功能的影响。方法：20例接受选择性冠脉搭桥术的患者随机分为2组，10例（A组）为体外循环下冠脉搭桥组，另10例（B组）为非体外循环下冠脉搭桥组，围术期48h内监测肾小球和肾小管功能的改变。结果：两组无住院死亡，心梗和急性肾功能不全，非体外循环冠脉搭桥组尿白蛋白、α1－微球蛋白和NAG较体外循环组明显降低（P＜0．01）。结论：非体外循环冠脉搭桥组较传统体外循环冠脉搭桥组明显减轻对肾功能的损伤。
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| 关 键 词： | 冠脉搭桥术 体外循环 尿白蛋白 α1－微球蛋白 NAG 肾功能 |
| 文章编号： | 0258-5898(2003)02-0162-03 |
| 修稿时间： | 2002年9月13日 |
Effects of On-pump Versus Off-pump Coronary Revascularization on Renal Function |
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| DU Qi-rong,SHAN Gen-fa,ZHANG Fu-xian,et al.Effects of On-pump Versus Off-pump Coronary Revascularization on Renal Function[J].Journal of Shanghai Jiaotong University:Medical Science,2003,23(2):162-164. |
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| Authors: | DU Qi-rong SHAN Gen-fa ZHANG Fu-xian |
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| Abstract: | Objective To investigate the effects on renal function in patients undergoing coronary revascularization with cardiopulmonary bypass (on -pump CABG) and those without cardiopulmonary bypass ( off - pump CABG). Methods Twenty patients undergoing elective CABG were divided into group A ( 10 on - pump CABG patients) and group B ( 10 off- pump CABG patients) . Glomerular and tubular functions were assessed up to 48h postoperatively. Results There were no hospital deaths, myocardial infarctions or acute renal failure in either group. We found that off - pump coronary revascularization induced less microalbuminuria, a1 - MG and NAG as compared with operations with CPB. Conclusion Off - pumpcoronary surgery significantly attenuates renal injury compared with conventional on - pump coronary artery bypass grafting. |
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| Keywords: | NAG |
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