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甲状腺相关性眼病炎性因素的研究进展
引用本文:程艺,晏立,饶杰,吴雅俊,吴娜,黄慧,李思瑜,施凌,吴晓蓉. 甲状腺相关性眼病炎性因素的研究进展[J]. 国际眼科杂志, 2020, 20(7): 1164-1166
作者姓名:程艺  晏立  饶杰  吴雅俊  吴娜  黄慧  李思瑜  施凌  吴晓蓉
作者单位:330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科;330000 中国江西省南昌市,南昌大学第一附属医院眼科
基金项目:国家自然科学基金(No.81760179,81360151); 江西省自然科学基金项目一般项目(No.20171BAB205046); 江西省教育厅科技技术研究项目重点项目(No.GJJ160033); 江西省科技支撑计划项目(No.20141BBG70027); 江西省教育厅科学技术研究项目一般项目(No.GJJ13147); 江西省卫生计生委科技计划普通科技计划(No.20185118,20141031); 江西省基础健康适宜技术星火推广计划(No.20188007)
摘    要:

甲状腺相关性眼病(thyroid-associated ophthalmopathy,TAO)是成人眼眶病中最常见的疾病,其眼部损害日益严重,对患者身心健康造成极大的伤害。TAO的发病机制十分复杂,目前还未完全阐明,经典理论为共抗原学说。鉴于现有治疗方案存在的弊端,研究与TAO相关的因素进而探求更好的治疗方法对TAO患者具有重要意义。近年来研究发现炎症反应与TAO关系密切,故本文就TAO相关炎性因素的研究做一综述。

关 键 词:甲状腺相关性眼病  炎性因子  炎症细胞
收稿时间:2019-09-27
修稿时间:2020-06-05

Research progress on inflammatory factors of thyroid-associated ophthalmopathy
Yi Cheng,Li Yan,Jie Rao,Ya-Jun Wu,Na Wu,Hui Huang,Si-Yu Li,Ling Shi and Xiao-Rong Wu. Research progress on inflammatory factors of thyroid-associated ophthalmopathy[J]. International Eye Science, 2020, 20(7): 1164-1166
Authors:Yi Cheng  Li Yan  Jie Rao  Ya-Jun Wu  Na Wu  Hui Huang  Si-Yu Li  Ling Shi  Xiao-Rong Wu
Affiliation:Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China,Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China and Department of Ophthalmology,the First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi Province, China
Abstract:Thyroid-associated ophthalmopathy(TAO)is the most common orbital disease in adults. Its ocular damage is becoming more and more serious, which causes great harm to the physical and mental health of patients. The pathogenesis of TAO is very complex and has not yet been fully elucidated. The classical theory is the theory of co-antigens. In view of the drawbacks of existing treatment schemes, it is of great significance to study the factors related to TAO and explore better treatment methods for TAO patients. In recent years, the relationship between inflammatory response and TAO has been found, therefore this article reviews the research on TAO-related inflammatory factors.
Keywords:thyroid-associated ophthalmopathy   inflammatory factors   inflammatory cells
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