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楮实子的化学成分研究
引用本文:熊山,;陈玉武,;叶祖光. 楮实子的化学成分研究[J]. 国外医药(植物药分册), 2009, 0(1): 34-36
作者姓名:熊山,  陈玉武,  叶祖光
作者单位:[1]中药复方新药开发国家工程研究中心,北京100075; [2]贵阳中医学院药学系,贵州贵阳550002; [3]中日友好医院临床医学研究所,北京100029
摘    要:目的对桑科构树属植物构树的果实——楮实子的化学成分进行研究。方法采用柱色谱法进行分离、精制,通过理化性质和波谱分析方法鉴定化合物的结构。结果从楮实子95%乙醇冷浸物中分离得到7个化合物,分别鉴定为胡萝5苷棕榈酸酯(Ⅰ)、胡萝卜苷(Ⅱ)、苯丙氨酸(Ⅲ)、色氨酸(Ⅳ)、壬二酸(Ⅴ)、β-谷甾醇(Ⅵ)、蔗糖(Ⅶ)。结论化合物Ⅰ、Ⅱ、Ⅲ、Ⅳ和Ⅴ均首次在楮实子中分得。

关 键 词:楮实子  胡萝卜苷棕榈酸酯  苯丙氨酸  色氨酸

Chemical constituents from fruit of Broussonetia papyrifera
Affiliation:XIONG Shan, CHEN Yu-wu, YE Zu-guang (1. State Research Center for Research and development of Traditional Chinese Medicine Multi-ingredient Drugs, Beijing 100076, China; 2. Department of Pharmacy, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China; 3. Institute of Clinical Medicine, China-Japan Friendship Hospital, Beijing 100029, China)
Abstract:Objective To study the chemical constituents of the fruit of Broussonetia papyrifera (L.) Vent. Methods Compounds were isolated and purified by silica column chromatography structures were identified by physicochemical properties and spectral analyses. Results , and the Sevene compounds, daucosterol palmitate ( Ⅰ ), daucosterol ( Ⅱ ), phenylalanine ( Ⅲ ), tryptophane ( Ⅳ ), azelaic acid ( Ⅴ ),β-sitosterol ( Ⅵ ), and sucrose (Ⅶ) were isolated and identified. Conclusion Compound Ⅰ,Ⅱ , Ⅳ , and Ⅴ are isolated from the fruit of B. papyrifera for the first time.
Keywords:fruit of Broussonetia papyrifera (L.) Vent.  daucosterol palmitate  phenylanine  tryptophane
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