白内障摘出联合人工晶状体（IOL）植入术及无晶状体眼行IOL二期植入术患儿术后眼前节结构特点

目的　观察白内障摘出术联合人工晶状体（intraocular lens，IOL）植入术或无晶状体眼行IOL二期植入术的患儿术后眼前节结构的特点。方法　收集2005年2月至2018年1月于盛京医院行白内障摘出术联合IOL植入术或无晶状体眼行IOL二期植入术的患儿41例（62眼）；根据手术方式分为一期IOL植入组25例（37眼）和二期IOL植入组16例（25眼）。另选取与末次随访时的儿童年龄与性别相匹配的正常眼儿童作为对照组。通过眼前节光学相干断层扫描仪测量中央角膜厚度（central corneal thickness，CCT）、前房深度（anterior chamber depth，ACD）及前房角（anterior chamber angle，ACA），通过UBM观察眼前节形态。结果　一期IOL植入组和相应对照组CCT分别为（542.62±31.79）μm和（539.35±30.10）μm，差异无统计学意义（P>0.05）；二期IOL植入组CCT为（573.56±46.58）μm，显著大于相应对照组（541.92±25.46）μm（P<0.01）。一期IOL植入组ACD为（3.37±0.38）mm，显著大于相应对照组（2.94±0.24）mm；二期IOL植入组ACD为（2.73±0.31）mm，显著小于相应对照组（3.03±0.30）mm（均为P<0.01）。一期和二期IOL植入组的ACA分别为（42.92±4.56）°和（40.58±6.84）°，均显著小于相应对照组ACA （48.73±7.49）°和（48.14±5.71）°（均为P<0.01）。一期IOL植入术后可见皮质增生主要位于IOL前方；二期IOL植入术后皮质增生主要位于IOL后方。结论　儿童白内障摘出术联合IOL植入术或无晶状体眼行IOL二期植入术后眼前节结构与正常儿童相比发生了改变。

Anterior segmental biometry characteristics of children patients following cataract extraction combined with intraocular lens (IOL) implantation or secondary IOL implantation in aphakic eyes

Objective　To analyse the anterior segmental biometry characteristics of children patients following cataract extraction combined with intraocular lens (IOL) implantation or secondary IOL implantation in aphakic eyes.Methods　Together 41 patients (62 eyes) of children patients who underwent cataract extraction combined with IOL implantation or secondary IOL implantation in aphakic eyes in Shengjing Hospital from February 2005 to January 2018 were included in this study.We divided them into 2 groups according to the operation method:primary IOL implantation group (37 eyes,25 patients) and secondary IOL implantation group (25 eyes,16 patients).The matched normal children were collected as the normal controls.Data on central corneal thickness (CCT),anterior chamber depth (ACD) and anterior chamber angle (ACA) were measured by anterior segment optical coherence tomography(AS-OCT).The morphology of the anterior segments was observed by ultrasound biomicroscopy(UBM).Results　CCT of primary IOL implantation group and the normal control group was (542.62±31.79)μm and (539.35±30.10)μm,respectively,with no significant difference (P>0.05).CCT of secondary IOL implantation group was (573.56±46.58)μm,which was significantly higher than that of the control group ［(541.92±25.46)μm］ (P<0.01).ACD of primary IOL implantation group was (3.37±0.38)mm,which was significantly greater than that of the control group ［(2.94±0.24)mm］ and ACD of secondary IOL implantation group was (2.73±0.31)mm,which was significantly smaller than that of the normal control group ［(3.03±0.30)mm］ (both P<0.01).ACA of primary and secondary IOL implantation groups was (42.92±4.56)°and (40.58±6.84)°,respectively,which were significantly smaller than those of the control group ［(48.73±7.49)°and (48.14±5.71)°］ (all P<0.01).Cortical hyperplasia was mainly located in front of IOL after primary IOL implantation,while after secondary IOL implantation,it was mainly located behind IOL.Conclusion　The anterior segmental biometry characteristics is different from those in children after cataract extraction combined with IOL implantation or secondary IOL implantation in aphakic eyes.