| 抗血管生成药物治疗恶性脑水肿的研究进展 |
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| 引用本文： | 马晓云,李全福,姜彩虹,陈 凤,乌雅罕,王文娟,乌云高娃,金高娃.抗血管生成药物治疗恶性脑水肿的研究进展[J].现代肿瘤医学,2019,0(20):3736-3742. |
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| 作者姓名： | 马晓云 李全福 姜彩虹 陈 凤 乌雅罕 王文娟 乌云高娃 金高娃 |
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| 作者单位： | 内蒙古医科大学鄂尔多斯临床医学院 鄂尔多斯市中心医院肿瘤科，内蒙古 鄂尔多斯 017000 |
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| 基金项目： | CSCO-先声抗肿瘤血管靶向治疗科研基金；北京医学奖励基金会肺癌医学青年专家委员会BEST基金（编号:YXJL-BEST-B-01） |
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| 摘 要： | 抗血管生成药物通过减少血管通透性和血脑屏障破坏，能有效减轻恶性脑水肿，缓解临床症状，改善患者生命质量。目前多种抗血管生成药物在治疗恶性脑水肿方面取得了积极的疗效，因此被认为是较糖皮质激素治疗恶性脑水肿更为安全、有效的治疗手段。
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| 关 键 词： | 脑水肿 抗血管生成药物 脑转移瘤 |
Advances in the treatment of malignant brain edema with angiogenesis inhibitor |
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| Ma Xiaoyun,Li Quanfu,Jiang Caihong,Chen Feng,Wu Yahan,Wang Wenjuan,Wu Yungaowa,Jin Gaowa.Advances in the treatment of malignant brain edema with angiogenesis inhibitor[J].Journal of Modern Oncology,2019,0(20):3736-3742. |
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| Authors: | Ma Xiaoyun Li Quanfu Jiang Caihong Chen Feng Wu Yahan Wang Wenjuan Wu Yungaowa Jin Gaowa |
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| Affiliation: | Oncology Department,Ordos School of Clinical Medicine,Inner Mongolia Medical University,Ordos Central Hospital,Inner Mongolia Ordos 017000，China． |
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| Abstract: | Angiogenesis inhibitor can effectively reduce malignant brain edema，relieve clinical symptoms and improve the quality of life of patients by reducing vascular permeability and the blood-brain barrier damage.At present，a variety of angiogenesis inhibitors have achieved a positive effect in the treatment of malignant brain edema，so it is considered to be a more safe and effective treatment than glucocorticoid in the treatment of malignant brain edema. |
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| Keywords: | brain edema anti-angiogenesis brain metastases |
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