胃癌腹膜转移患者行胃癌切除术及术后化疗的生存分析

目的:探讨胃癌腹膜转移患者行手术及术后化疗的意义。方法:回顾性分析胃癌腹膜转移病例89例，收集有效随访病例的相关术前临床和病理学资料、术中探查所见转移方式、手术方式、术后处理措施等数据。结果:通过对患者临床病理学特征进行单因素分析显示，手术方式（P=0.004）、化疗（P=0.003）、腹膜转移方式 (P<0.05)、Borrmann分型 (P<0.05)对胃癌腹膜转移的预后生存具有显著性影响。结论:对于胃癌腹膜转移患者，无论患者转移程度如何，如果没有绝对手术禁忌证，建议行胃癌切除D1淋巴结清扫，术后配合化疗。

Survival analysis of gastric cancer patients with peritoneal metastasis after gastrectomy and postoperative chemotherapy

Objective:To investigate the significance of operation and postoperative chemotherapy for patients with peritoneal metastasis of gastric cancer.Methods: 89 cases of peritoneal metastasis of gastric cancer were retrospectively analyzed.The preoperative clinical and pathological data，the mode of metastasis，the choice of operative methods，and the treatment measures were collected.Results:Univariate analysis of the clinicopathological features of the patients showed that the prognosis and survival of gastric cancer with peritoneal metastasis were significantly affected by operation (P=0.004)，chemotherapy (P=0.003)，peritoneal metastasis (P<0.05) and Borrmann classification (P<0.05).Conclusion:For gastric cancer patients with peritoneal metastasis，regardless of the degree of metastasis，if there is no absolute surgical contraindication，gastrectomy D1 lymph node dissection is recommended，postoperative chemotherapy.