| 2,2-二(3-氨基-4-羟基)苯基丙烷的合成与结构表征 |
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| 引用本文： | 赵芳,周莹,孙汉洲,胡云楚.2,2-二(3-氨基-4-羟基)苯基丙烷的合成与结构表征[J].精细化工中间体,2004,34(1):18-20. |
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| 作者姓名： | 赵芳 周莹 孙汉洲 胡云楚 |
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| 作者单位： | 中南林学院,应用化学研究所,湖南,株洲,412006 |
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| 基金项目： | :中南林学院青年科研基金 (项目编号 0 480 ) |
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| 摘 要： | 分别在Pd/C、FeOOH和FeCl3·6H2O/C三种不同催化剂存在下,由水合肼还原2,2 二(4 羟基 3 硝基)苯基丙烷(1)合成了2,2 二(3 氨基 4 羟基)苯基丙烷,筛选出成本低、收率高的理想催化剂为FeCl3·6H2O/C。当物料配比n(水合肼):n(1)=5:1,反应起始温度为70℃,反应时间为80min时,收率为93 0%。产物经重结晶纯化后,由元素分析、红外光谱、核磁共振谱和质谱对其结构进行了表征,确证了产物的结构。
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| 关 键 词： | 2 2-二(4-羟基-3-硝基)苯基丙烷 2 2-二(3-氨基-4-羟基)苯基丙烷 水合肼 还原 FeCl36H2O/C催化剂。 |
| 文章编号： | 1009-9212(2004)01-0018-03 |
| 修稿时间： | 2003年9月15日 |
The Synthesis and Structural Characterization of 2,2-Bis (3-Amido-4-Hydroxyphenyl)-Propane |
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| ZHAO Fang,ZHOU Ying,SUN Han-zhou,HU Yun-chu.The Synthesis and Structural Characterization of 2,2-Bis (3-Amido-4-Hydroxyphenyl)-Propane[J].Fine Chemical Intermediates,2004,34(1):18-20. |
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| Authors: | ZHAO Fang ZHOU Ying SUN Han-zhou HU Yun-chu |
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| Abstract: | 2,2-Bis(3-amido-4-hydroxyphenyl)-propane was synthesized by catalytic reduction of 2,2-Bis(4-hydroxy-3-nitrophenyl)-propane(1) with hydrazine hydrate in the presence of Pd/C,FeOOH and FeCl_3.6H_2O/C respectively. The results showed that the ideal catalyst was FeCl_3.6H_2O/C which gave high yield and had low cost. The yield was 93% when n (hydrazine hydrate):n(1)=5:1,temperature 70?℃, and reaction time 80?min. The structure of the product, which was crystallized, was certified by elementary analysis, IR,~1HNMR,~(13)CNMR and MS. |
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| Keywords: | 2 2-Bis(3-amido-4-hydroxyphenyl)-propane 2 2-Bis(4-hydroxy-3-nitrophenyl)-propane hydrazine hydrate catalytic reduction |
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