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外科创伤后炎性反应和免疫抑制
引用本文:何亮,钱燕宁. 外科创伤后炎性反应和免疫抑制[J]. 医学综述, 2007, 13(15): 1121-1123
作者姓名:何亮  钱燕宁
作者单位:1. 南京医科大学第二附属医院麻醉科,南京,210011
2. 南京医科大学第一附属医院麻醉科,南京,210029
基金项目:江苏省医学重点人才基金
摘    要:研究证实外科创伤后机体的免疫系统功能受到抑制,反映在创伤早期的过度炎性反应和随后的细胞免疫抑制。术后免疫系统功能紊乱是术后感染,败血症和多器官功能衰竭等并发症的发病原因之一。临床医师通过免疫调节可改善创伤后免疫抑制。本文概述外科创伤介导的免疫抑制的机制和免疫调节治疗研究进展。

关 键 词:创伤和损伤  炎性反应  免疫抑制
文章编号:1006-2084(2007)15-1121-03
修稿时间:2006-10-22

Surgical Trauma-induced Inflammatory Reaction and Immunosuppression
HE Liang,QIAN Yan-ning. Surgical Trauma-induced Inflammatory Reaction and Immunosuppression[J]. Medical Recapitulate, 2007, 13(15): 1121-1123
Authors:HE Liang  QIAN Yan-ning
Abstract:Studies have testified that immune system of the body was suppressed afer having surgical trauma,which can be shown by the excessive inflammatory reaction and the following cell immunosuppression during early period.Functional disorder of immune system after operation is the main cause of complications including postoperation infection,septicemia,multiple organ failure and so on.Clinical doctors can improve post trauma immunosuppression by immunoloregulation.This article reviews study progresses of mechanism of immunosupression induced by surgical trauma and its immunotherapy.
Keywords:Trauma and injury  Inflammatory reaction  Immunosuppression
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