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CT时间减影技术在肺结节检测中的应用
引用本文:王云龙,范丽,望云,管宇,夏艺,李琼,萧毅,刘士远. CT时间减影技术在肺结节检测中的应用[J]. 实用放射学杂志, 2017, 0(8): 1276-1280. DOI: 10.3969/j.issn.1002-1671.2017.08.030
作者姓名:王云龙  范丽  望云  管宇  夏艺  李琼  萧毅  刘士远
作者单位:1. 第二军医大学附属长征医院影像诊断科,上海 200003;解放军第88医院影像诊断科,山东 泰安 271001;2. 第二军医大学附属长征医院影像诊断科,上海,200003
基金项目:国家自然科学基金面上项目(81370035),上海市科委重大生物医药专项(13411950100),浦江上海人才项目(15PJD002),国家自然科学基金重点项目(81230030),国家重点研发计划政府间科技合作项目(2016YFE0103000)
摘    要:目的 探讨CT时间减影技术在检测肺结节中的应用价值.方法 回顾性分析80例CT图像(每例均有过去和当前的CT图像)和相应的CT减影图像,其中30例有肺结节(共75个结节)作为研究组,50例无肺结节作为对照组.2名高年资与2名低年资放射科医师分别首先分析普通CT图像,然后再同时分析普通图像与CT减影图像.阅读时诊断是否存在较前次增大、实性成分增多或者新发的结节并对诊断的肯定度进行评分.观察的结果采用受试者工作特征(ROC)曲线进行分析.结果 4名放射科医师使用CT减影图像前后的平均ROC曲线下面积(AUC)分别为0.860和0.925,两者有统计学差异(P<0.01).使用CT减影图像后,肺结节检出率由77.3%(58/75)提高到89.3%(67/75).结论 CT时间减影技术可以显著提高放射科医师的肺结节检出率,尤其是对靠近肺门的亚实性小结节,而且低年资医师受益更多.

关 键 词:肺肿瘤  图像处理  计算机辅助

CT temporal subtraction for detection of lung nodules
WANG Yunlong,FAN Li,WANG Yun,GUAN Yu,XIA Yi,LI Qiong,XIAO Yi,LIU Shiyuan. CT temporal subtraction for detection of lung nodules[J]. Journal of Practical Radiology, 2017, 0(8): 1276-1280. DOI: 10.3969/j.issn.1002-1671.2017.08.030
Authors:WANG Yunlong  FAN Li  WANG Yun  GUAN Yu  XIA Yi  LI Qiong  XIAO Yi  LIU Shiyuan
Abstract:Objective To evaluate the effect of CT temporal subtraction(TS) for detection of lung nodules.Methods 80 cases of CT images (current and previous CT images) and corresponding CT TS images were presented, which included 30 cases with nodules(75 nodules) and 50 controls.4 observers, including 2 radiologists and 2 residents, indicated their confidence level regarding the presence of a new emerging or larger or solid component than before,which first used standard CT images, then with the addition of CT TS images.Receiver operating characteristic(ROC) curve analysis was used to evaluate the observers' performance.Results The mean value of the area under the ROC curve (AUC) were 0.860 and 0.925 for four observers without and with TS images,respectively(P<0.01).Average sensitivity for detection of lung nodules was improved from 77.3%(58/75) to 89.3%(67/75) by using CT TS images.Conclusion The use of CT TS images can significantly improve radiologists' performance for detection of lung nodules,especially when a small size solid or subsolid nodule presents near the pulmonary hilum.CT TS is more helpful for residents.
Keywords:lung tumor  image processing  computer-aided
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