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幽门螺杆菌粘附作用的体外研究
引用本文:傅冷西,梁平. 幽门螺杆菌粘附作用的体外研究[J]. 福建医科大学学报, 1993, 0(2)
作者姓名:傅冷西  梁平
作者单位:福建医学院基础外科研究室,福建医学院电子显微镜室
摘    要:置幽门螺杆菌(HP)悬液于含人喉癌上皮细胞(Hep-2)或人胃癌上皮细胞(MKN-28)的培养瓶内,经2h或3.5h培养后观察HP对细胞的粘附情况。结果发现HP能成丛地粘附在上皮细胞表面,少数侵入胞浆内。HP对MKN-28粘附率明显高于对Hep-2细胞者。随菌龄的延长或菌株的变异,HP的粘附作用明显减弱。1%D-甘露糖对HP的粘附性有部分阻抑作用。

关 键 词:幽门螺杆菌  人喉癌上皮细胞株  人胃癌细胞株  粘附作用

Study on Helicobacter Pylori Adherence in Vitro
Fu Lengxi,Liang Ping. Study on Helicobacter Pylori Adherence in Vitro[J]. Journal of Fujian Medical University, 1993, 0(2)
Authors:Fu Lengxi  Liang Ping
Abstract:Helicobacter pylori (HP) suspension was added to Hep-2 cells derived from human laryngeal carcinoma or MKN-28 cells derived from human gastric carcinoma. After 2 h or 3. 5 h incubation,most HP were adherent to the surface of Hep-2 or MKN-28 cells and some HP invaded into their cytoplasma. The adherence rate to MKN-28 cells is much higher than that to Hep-2 cells. Adherence of HP to the epithelial cells was markedly impaired with their age or morphological variation. Adherence of HP was some what restrained by pre-treatment of Hep-2 cells with 1%D-mannose.
Keywords:Helicobacter pylori  Hep-2 cells  MKN-28 cells  adherence
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