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不同血浆靶浓度瑞芬太尼在高血压患者全麻诱导中的应用
引用本文:贺菲,申黎光,郑涛.不同血浆靶浓度瑞芬太尼在高血压患者全麻诱导中的应用[J].华夏医学,2009,22(3):402-404.
作者姓名:贺菲  申黎光  郑涛
作者单位:桂林市第二人民医院麻醉科,广西桂林,541001
摘    要:目的:比较不同血浆靶浓度瑞芬太尼在高血压患者全麻诱导中的应用.方法:选择择期全麻手术高血压患者60例,随机分为3组(n=20).分别设定瑞芬太尼血浆靶浓度为1、3、5ng/ml(R1、R3、R5),异丙酚血浆浓度为3μg/ml,与瑞芬太尼同时输注,患者意识消失后气管插管,记录患者意识消失时间及插管前后的收缩压、舒张压、平均动脉压、心率.结果:R1组插管后SBP、SDP、MAP、HR均高于插管前,而R3和R5组插管后SBP、SDP、MAP虽有所上升,但较诱导前低,差异有显著性(P<0.05).结论:使用靶控输注瑞芬太尼与异丙酚在高血压患者进行全麻诱导,两者靶控浓度分别为3 ng/ml与3/μg/ml较适宜.

关 键 词:靶控输注  瑞芬太尼  异丙酚  高血压  静脉麻醉

Application of different blood plasma target concentration of remifentanil in hypertensive patients in anesthesia induction
HE Fei,SHEN Li-guang,ZHENG Tao.Application of different blood plasma target concentration of remifentanil in hypertensive patients in anesthesia induction[J].Acta Medicinae Sinica,2009,22(3):402-404.
Authors:HE Fei  SHEN Li-guang  ZHENG Tao
Abstract:Objective: To observe the anesthetic effects of different blood plasma target concentration of remifentanil in hypertension patients.Methods: Sixty hypertension patients for scheduled surgery were randomly assigned to three groups(n=20),setting remifentanil blood plasma target level was 1,3,5ng/ml(R1,R3,R5),respectively,propofol's blood plasma target level was 3ug/ml intravenous infusion simultaneously.After unconsiousness then endotracheal intubation,the time of unconsiousness was recorded,SBP,DBP,MAP and ...
Keywords:target controlled infusion  remifentanil  propofol  hypertension  intravenous anesthesia  
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