建康成年男性血脂随年龄的变化规律及血脂异常的分布特征

目的：探讨健康成年男性血脂随年龄的变化规律及血脂异常的患病率与分布特征。方法：用ELISA方法测定489名20～80岁男性志愿者的血清三酰甘油（TG）、血清总胆固醇（TC）、血清高密度脂蛋白胆固醇（HDL）和血清低密度脂蛋白胆固醇（LDL）。结果：①直线相关分析显示，TG、HDL与年龄无显著相关，LDL、TC与年龄呈正相关（P〈0．05），校正是否吸烟后，LDL、TC与年龄相关性仍存在，相关系数为0．123～0．173（P〈0．05）。②总体人群血脂异常检出率为57．8％，20岁以后即有40％以上人群出现血脂异常，并随年龄增加，30—69岁年龄组的检出率为54．3％～68．8％，70岁以后下降。③血脂异常的类型以TC异常与TG异常为多，其余依次为高LDL血症、高TC合并高TG血症、低HDL血症，分别为42．0％、28．7％、24．8％、19．1％、12．7％。结论：①成年健康男子血脂异常随年龄增长而呈升高趋势。②血脂异常的类型以TC异常与TG异常为多。

The study of the healthy adult males the changes of blood lipids with age and the prevalence and distribution characteristics of dyslipidemia in normal men

Objective： To study healthy adult males the changes of blood lipids with age and the prevalence and distribu- tion characteristics of dyslipidemia in normal men aged 20-80 years old. nethods：ELISA method was used in measuring serum triglyceride（TG）, serum total cholesterol（TC）, serum high-density lipoprotein cholesterol （HDL） and serum low-density lipoprotein cholesterol （LDL） in 489 normal male volunteers aged 20-80.Results：①LDL and TC were positively correlated with age （P〈0.05） while no significant relation were found between TG, HDL and age.After correcting smoking factor, there are still a correlation between LDL and TC with age （r= -0.123-0.173, P〈0.05）.②The rate of dyslipidemia among to- tal volunteers population was 57.8%. All subjects were stratified by 10-year age groups, the detection prevalence of dys- lipidemia was 40% in〉20 years-old group and increasing with age. in the 30-69 years of group the prevalence fluctuate between 54.3% to 68.8% ,decreasing after the age of 70. ③TC and TG abnormalities were more than the other type of dyslipidemia followed by high LDL dyslipidemia,high-TC combined high TG and low HDL hyperlipidemia,with the detection prevalence respectively 42%, 28.7%, 24.8%, 19.1%, 12.7%.Conclusion： ①It showes the growth of abnormal blood lipid increase with age adult healthy men.②The main type of dyslipidemia are TC and TG abnormalities.