| 2-氰基-4′-甲基联苯的合成研究 |
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| 引用本文： | 余红霞. 2-氰基-4′-甲基联苯的合成研究[J]. 精细化工中间体, 2003, 0(6) |
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| 作者姓名： | 余红霞 |
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| 作者单位： | 武汉化工学院化工与制药学院 湖北武汉430073 |
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| 摘 要： | 以溴化亚铜为催化剂,将邻苯甲腈与对溴甲苯偶联制备了合成沙坦类药物的关键中间体2 氰基 4′ 甲基联苯,收率50%。
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| 关 键 词： | 2-氰基-4′-甲基联苯 合成 溴化亚铜 |
The Synthesis of 2-Cyano-4’-Methyl Phenylbenzene. |
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| YU Hong xia.. The Synthesis of 2-Cyano-4’-Methyl Phenylbenzene.[J]. Fine Chemical Intermediates, 2003, 0(6) |
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| Authors: | YU Hong xia. |
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| Abstract: | cyano 4’ methyl phenylbenzene, a key intermediate of Sartan drug, was synthesized from 4 bromotoluene and 2 bromobenzonitrile in the present of cuprous bromide as a catalyst. The yield is 50%. |
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| Keywords: | cyano-4’-methyl phenylbenzene synthesis cuprous bromide |
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