血清睾酮、雌二醇水平与女性尿失禁的相关性研究

目的 研究血清睾酮、雌二醇水平对女性尿失禁严重程度的影响。方法 回顾性分析2009年5月~2016年5月本院收治的264例女性尿失禁患者的临床资料，根据尿失禁发病特点，分为压力性尿失禁、急迫性尿失禁、混合性尿失禁，检测尿失禁患者血清睾酮、雌二醇水平，分析血清睾酮、雌二醇水平与女性尿失禁的相关性。结果 压力、急迫和混合性尿失禁女性的血清睾酮、雌二醇水平低于无尿失禁女性，差异有统计学意义（P＜0.05）；压力、急迫和混合性尿失禁女性的血清睾酮、雌二醇水平比较，差异无统计学意义（P＞0.05）。血清低睾酮和低雌二醇水平与女性压力性尿失禁呈正相关（r=0.22，0.27，P＜0.05）。结论 血清睾酮、雌二醇水平低下的女性比正常女性尿失禁的发病率增加，血清睾酮、雌二醇水平低下与女性尿失禁增加有相关性。

Correlation between Serum Testosterone and Estradiol Levels and Female Urinary Incontinence

Objective To investigate the correlation of serum testosterone and estradiol levels with urinary incontinence in women. Methods 264 urinary incontinence in women were selected and divided into stress urinary incontinence, urge incontinence and mixed incontinence. The levels of serum testosterone and estradiol in patients with urinary incontinence were detected，the correlation between serum levels of testosterone and estradiol and female urinary incontinence was analyzed. Results The levels of serum testosterone and estradiol in women with stress, urgency and mixed incontinence were significantly lower than those in women without urinary incontinence, with statistical difference (P<0.05). There was no significant difference in serum testosterone and estradiol levels between women with stress, urgency and mixed urinary incontinence (P>0.05). Serum low testosterone and low estradiol levels were positively correlated with female stress urinary incontinence (r=0.22,0.27,P<0.05).Conclusion Women with low levels of serum testosterone and estradiol have an increased incidence of urinary incontinence compared with normal women, and low serum testosterone and estradiol levels are associated with increased urinary incontinence in women.