泮托拉唑治疗消化性溃疡合并上消化道出血的临床价值评价

目的 观察泮托拉唑治疗消化性溃疡合并上消化道出血的临床疗效。方法 选取2015年5月~2018年3月我院收治的100例消化性溃疡合并上消化道出血患者为研究对象，随机分为实验组和对照组，各50例。对照组患者采用奥美拉唑治疗，实验组患者采用泮托拉唑治疗。比较两组临床疗效及不良反应情况。结果 实验组治疗总有效率高于对照组（96.00% vs 80.00%），差异有统计学意义（P＜0.05）；实验组患者不良反应发生率低于对照组（6.00% vs 24.00%），差异有统计学意义（P＜0.05）。结论 泮托拉唑治疗消化性溃疡合并上消化道出血临床疗效可靠，安全性高。

Clinical Value of Pantoprazole in the Treatment of Peptic Ulcer Complicated with Upper Gastrointestinal Bleeding

Objective To observe the clinical efficacy of pantoprazole in the treatment of peptic ulcer with upper gastrointestinal bleeding.Methods 100 patients with peptic ulcer complicated with upper gastrointestinal bleeding admitted to our hospital from May 2015 to March 2018 were randomly divided into experimental group and control group, 50 cases each. Patients in the control group were treated with omeprazole, and patients in the experimental group were treated with pantoprazole. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate of the experimental group was higher than that of the control group (96.00% vs 80.00%), the difference was statistically significant (P<0.05). The incidence of adverse reactions in the experimental group was lower than that of the control group (6.00% vs 24.00%)，the difference was statistically significant (P<0.05). Conclusion Pantoprazole is a reliable and safe treatment of peptic ulcer with upper gastrointestinal bleeding.