| Studies on the Syntheses and Biological Activities of 3-Aryl-6-(1,1'-biphenyl-4-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines |
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| 作者姓名： | YE Xiao-qin ZHANG Li-xue ** ZHANG An-jiang CHEN Xian-xing and ZHANG Zi-yi . |
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| 作者单位： | YE Xiao-qin 1，2，ZHANG Li-xue 1**，ZHANG An-jiang 1，CHEN Xian-xing 1 and ZHANG Zi-yi 31. Department of Chemistry，Wenzhou Teachers' College，Wenzhou 325003，P. R. China; 2. Chemistry Teaching and Research Section，Wenzhou Medical College，Wenzhou 325003，P. R. China3. Department of Chemistry，Lanzhou University，Lanzhou 730000，P. R. China |
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| 基金项目： | Supported by the National Natural Science Foundation of China( No.2 982 0 0 4),the U niversity Backbone TeachersFoundation of the Education Ministry of China and Zhejiang Province Education Department |
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| 摘 要： | IntroductionAmongst various heterocycles 3 ,6 -disubstituted- 7H- 1 ,2 ,4- triazolo3 ,4- b]1 ,3 ,4]thiadiazines have received considerable attentionduring the lasttwo decades as potentially biologicalactive agents1,2 ] . A literature survey indicated thatthis kind of N - bridged heterocycles displayed awide spectrum of biological properties,such asantimicrobial3] ,antibacterial,antifungal4 ] ,antiinflammatory5] ,diuretic6 ] ,anthelmintic,andanalgesic7] . They can also be used as the p…
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Studies on the Syntheses and Biological Activities of 3-Aryl-6-(1,1'-biphenyl-4-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines |
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| YE Xiao-qin ,,ZHANG Li-xue **,ZHANG An-jiang ,CHEN Xian-xing and ZHANG Zi-yi ..Studies on the Syntheses and Biological Activities of 3-Aryl-6-(1,1''''-biphenyl-4-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines[J].Chemical Research in Chinese University,2002,18(4). |
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| Authors: | YE Xiao-qin ZHANG Li-xue ZHANG An-jiang CHEN Xian-xing ZHANG Zi-yi |
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| Abstract: | A series of novel 3-aryl-6-(1,1'-biphenyl-4-yl)-7H-1,2,4-triazolothiadiazines was synthesized by means of the reactions between 3-aryl-4-amino-5-mercapto-1,2,4-triazoles and 2-bromo-4'-phenylacetophenone. The structures of all the title compounds have been confirmed by virtue of elemental analysis, IR, 1H NMR, 13C NMR and mass spectra. The characteristics of 13C NMR peaks of the compounds were investigated. The plant growth regulating effects of those compounds were also determined. |
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| Keywords: | H-1 2 4-Triazolothiadiazines Synthesis Biological activity |
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